ITGA7 Antikörper

Produktnummer ABIN6292834

Produktdetails anti-ITGA7 Antikörper

Target: ITGA7 (Integrin, alpha 7 (ITGA7))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ITGA7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of human ITGA7

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000

Kommentare:

Isoforms containing segment A are predominantly expressed in skeletal muscle, Isoforms containing segment B are abundantly expressed in skeletal muscle, moderately in cardiac muscle, small intestine, colon, ovary and prostate and weakly in lung and testes, Isoforms containing segment X2D are expressed at low levels in fetal and adult skeletal muscle and in cardiac muscle, but are not detected in myoblasts and myotubes, In muscle fibers isoforms containing segment A and B are expressed at myotendinous and neuromuscular junctions

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20C. Avoid freeze / thaw cycles.

Details zu ITGA7

Target: ITGA7 (Integrin, alpha 7 (ITGA7))

Andere Bezeichnung: ITGA7 (ITGA7 Produkte)

Synonyme: [a]7 antikoerper, alpha7 antikoerper, integrin alpha 7 antikoerper, integrin subunit alpha 7 antikoerper, Itga7 antikoerper, ITGA7 antikoerper

Hintergrund: The protein encoded by this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. They mediate a wide spectrum of cell-cell and cell-matrix interactions, and thus play a role in cell migration, morphologic development, differentiation, and metastasis. This protein functions as a receptor for the basement membrane protein laminin-1. It is mainly expressed in skeletal and cardiac muscles and may be involved in differentiation and migration processes during myogenesis. Defects in this gene are associated with congenital myopathy. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

Molekulargewicht: 128.948 kDa

Gen-ID: 3679

UniProt: Q13683

Pathways: Integrin Complex