ANKHD1 Antikörper

Produktnummer ABIN6292808

Produktdetails anti-ANKHD1 Antikörper

Target: ANKHD1 (Ankyrin Repeat and KH Domain Containing 1 (ANKHD1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ANKHD1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of human ANKHD1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000
IHC 1:50 - 1:200

Kommentare:

Ubiquitous with high expression in cervix, spleen and brain, Expressed in hematopoietic cells with increased expression in leukemia cells, Isoform 2 is highly expressed in spleen with almost no expression in muscle and brain

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20C. Avoid freeze / thaw cycles.

Details zu ANKHD1

Target: ANKHD1 (Ankyrin Repeat and KH Domain Containing 1 (ANKHD1))

Andere Bezeichnung: ANKHD1 (ANKHD1 Produkte)

Synonyme: 1110004O12Rik antikoerper, 4933432B13Rik antikoerper, 9130019P20Rik antikoerper, A530027J04Rik antikoerper, A630021B20Rik antikoerper, AA571404 antikoerper, Mask antikoerper, mFLJ00246 antikoerper, mKIAA1085 antikoerper, MASK antikoerper, VBARP antikoerper, ankyrin repeat and KH domain containing 1 antikoerper, Ankhd1 antikoerper, ANKHD1 antikoerper

Hintergrund: This gene encodes a protein with multiple ankyrin repeat domains and a single KH-domain. The protein is thought to function as a scaffolding protein, and it may be involved in the regulation of caspases and thereby play an antiapoptotic role in cell survival. Alternative splicing results in multiple transcript variants, one of which generates a fusion transcript (MASK-BP3) with the downstream eIF4E-binding protein 3 (EIF4EBP3) gene, resulting in a protein comprised of the ANKHD1 sequence for the majority of the protein and a different C-terminus due to an alternate reading frame for the EIF4EBP3 segments.

Molekulargewicht: 269.458 kDa

Gen-ID: 404734

UniProt: Q8IWZ3