KRT81 Antikörper

Produktnummer ABIN6292166

Produktdetails anti-KRT81 Antikörper

Target: KRT81 (Keratin 81 (KRT81))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KRT81 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Affinity purification

Immunogen: Recombinant Protein of human KRT81

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000

Kommentare:

Abundantly expressed in the differentiating cortex of growing (anagen) hair, Expression is restricted to the keratinocytes of the hair cortex and is absent from inner root sheath and medulla, Expressed in malignant lymph node tissue in breast carcinoma tissue

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20C. Avoid freeze / thaw cycles.

Details zu KRT81

Target: KRT81 (Keratin 81 (KRT81))

Andere Bezeichnung: KRT81 (KRT81 Produkte)

Synonyme: KRT81 antikoerper, KRTHB5 antikoerper, HB1 antikoerper, Hb-1 antikoerper, KRTHB1 antikoerper, MLN137 antikoerper, ghHkb1 antikoerper, hHAKB2-1 antikoerper, AA589625 antikoerper, Krt2-19 antikoerper, keratin 81 antikoerper, keratin, type II cuticular Hb1 antikoerper, keratin 85 antikoerper, KRT81 antikoerper, LOC100012075 antikoerper, LOC100092864 antikoerper, LOC100394162 antikoerper, LOC100481102 antikoerper, LOC100526784 antikoerper, KRT85 antikoerper, Krt81 antikoerper

Hintergrund: The protein encoded by this gene is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5. All hair keratins are expressed in the hair follicle, this hair keratin, as well as KRTHB3 and KRTHB6, is found primarily in the hair cortex. Mutations in this gene and KRTHB6 have been observed in patients with a rare dominant hair disease, monilethrix.

Molekulargewicht: 54.928 kDa

Gen-ID: 3887

UniProt: Q14533