S100A12 Antikörper

Produktnummer ABIN6291358

Produktdetails anti-S100A12 Antikörper

Target: S100A12 (S100 Calcium Binding Protein A12 (S100A12))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser S100A12 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of human S100A12

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:50 - 1:100

Kommentare:

Predominantly expressed by neutrophils, monocytes and activated macrophages, Expressed by eosinophils and macrophages in asthmatic airways in regions where mast cells accumulate, Found in high concentrations in the serum of patients suffering from various inflammatory disorders, such as rheumatoid arthritis, psoriatic arthritis, Crohn's disease, ulcerative colitis, and Kawasaki disease

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20C. Avoid freeze / thaw cycles.

Details zu S100A12

Target: S100A12 (S100 Calcium Binding Protein A12 (S100A12))

Andere Bezeichnung: S100A12 (S100A12 Produkte)

Synonyme: CAAF1 antikoerper, CAGC antikoerper, CGRP antikoerper, ENRAGE antikoerper, MRP-6 antikoerper, MRP6 antikoerper, p6 antikoerper, CO-AG antikoerper, EN-RAGE antikoerper, S100 calcium binding protein A12 antikoerper, protein S100-A12 antikoerper, S100A12 antikoerper, LOC101103771 antikoerper

Hintergrund: The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein is proposed to be involved in specific calcium-dependent signal transduction pathways and its regulatory effect on cytoskeletal components may modulate various neutrophil activities. The protein includes an antimicrobial peptide which has antibacterial activity.

Molekulargewicht: 10.575 kDa

Gen-ID: 6283

UniProt: P80511

Pathways: Toll-Like Receptors Cascades, S100 Proteine