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CysLTR1 Antikörper

CYSLTR1 Reaktivität: Human, Maus, Ratte WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6291346
  • Target Alle CysLTR1 (CYSLTR1) Antikörper anzeigen
    CysLTR1 (CYSLTR1) (Cysteinyl Leukotriene Receptor 1 (CYSLTR1))
    Reaktivität
    • 45
    • 6
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 44
    • 1
    Kaninchen
    Klonalität
    • 45
    Polyklonal
    Konjugat
    • 30
    • 5
    • 3
    • 3
    • 2
    • 2
    Dieser CysLTR1 Antikörper ist unkonjugiert
    Applikation
    • 35
    • 25
    • 19
    • 10
    • 10
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Aufreinigung
    Affinity purification
    Immunogen
    Recombinant protein of human CYSLTR1
    Isotyp
    IgG
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  • Applikationshinweise
    WB 1:500 - 1:2000
    Kommentare

    Widely expressed, with highest levels in spleen and peripheral blood leukocytes, Lower expression in several tissues, such as lung (mostly in smooth muscle bundles and alveolar macrophages), placenta, small intestine, pancreas, colon and heart

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20C. Avoid freeze / thaw cycles.
  • Target
    CysLTR1 (CYSLTR1) (Cysteinyl Leukotriene Receptor 1 (CYSLTR1))
    Andere Bezeichnung
    CYSLTR1 (CYSLTR1 Produkte)
    Synonyme
    zgc:112062 antikoerper, CYSLTR1 antikoerper, CYSLT1 antikoerper, CYSLT1R antikoerper, CYSLTR antikoerper, HMTMF81 antikoerper, BB147369 antikoerper, CysLT1R antikoerper, Cyslt1 antikoerper, cysLT1R antikoerper, cysteinyl leukotriene receptor 1 antikoerper, cysltr1 antikoerper, CYSLTR1 antikoerper, Cysltr1 antikoerper, LOC100338776 antikoerper
    Hintergrund
    This gene encodes a member of the G-protein coupled receptor 1 family. The encoded protein is a receptor for cysteinyl leukotrienes, and is involved in mediating bronchoconstriction via activation of a phosphatidylinositol-calcium second messenger system. Activation of the encoded receptor results in contraction and proliferation of bronchial smooth muscle cells, eosinophil migration, and damage to the mucus layer in the lung. Upregulation of this gene is associated with asthma and dysregulation may also be implicated in cancer. Alternative splicing results in multiple transcript variants.
    Molekulargewicht
    38.541 kDa
    Gen-ID
    10800
    UniProt
    Q9Y271
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