PCDHGA1 Antikörper

Produktnummer ABIN6291192

Produktdetails anti-PCDHGA1 Antikörper

Target: PCDHGA1 (Protocadherin gamma A1 (PCDHGA1))

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PCDHGA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Affinity purification

Immunogen: Recombinant Protein of human PCDHGA1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20C. Avoid freeze / thaw cycles.

Details zu PCDHGA1

Target: PCDHGA1 (Protocadherin gamma A1 (PCDHGA1))

Andere Bezeichnung: PCDHGA1 (PCDHGA1 Produkte)

Synonyme: PCDH-GAMMA-A1 antikoerper, protocadherin gamma subfamily A, 1 antikoerper, protocadherin gamma-C5 antikoerper, PCDHGA1 antikoerper, LOC478038 antikoerper, Pcdhga1 antikoerper

Hintergrund: This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.

Molekulargewicht: 101.226 kDa

Gen-ID: 56114

UniProt: Q9Y5H4