C10orf2 Antikörper

Produktnummer ABIN6290656

Produktdetails anti-C10orf2 Antikörper

Target: C10orf2 (C10ORF2) (Chromosome 10 Open Reading Frame 2 (C10ORF2))

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser C10orf2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Affinity purification

Immunogen: Synthetic peptide of human C10orf2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000

Kommentare:

High relative levels in skeletal muscle, testis and pancreas, Lower levels of expression in the heart, brain, placenta, lung, liver, kidney, spleen, thymus, prostate, ovary, small intestine, colon and leukocytes, Expression is coregulated with MRPL43

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20C. Avoid freeze / thaw cycles.

Details zu C10orf2

Target: C10orf2 (C10ORF2) (Chromosome 10 Open Reading Frame 2 (C10ORF2))

Andere Bezeichnung: TWNK (C10ORF2 Produkte)

Synonyme: ATXN8 antikoerper, IOSCA antikoerper, MTDPS7 antikoerper, PEO antikoerper, PEO1 antikoerper, PEOA3 antikoerper, SANDO antikoerper, SCA8 antikoerper, TWINL antikoerper, C6H10orf2 antikoerper, D19Ertd626e antikoerper, Twinl antikoerper, twinkle mtDNA helicase L homeolog antikoerper, twinkle mtDNA helicase antikoerper, twnk.L antikoerper, TWNK antikoerper, Twnk antikoerper

Hintergrund: This gene encodes a hexameric DNA helicase which unwinds short stretches of double-stranded DNA in the 5' to 3' direction and, along with mitochondrial single-stranded DNA binding protein and mtDNA polymerase gamma, is thought to play a key role in mtDNA replication. The protein localizes to the mitochondrial matrix and mitochondrial nucleoids. Mutations in this gene cause infantile onset spinocerebellar ataxia (IOSCA) and progressive external ophthalmoplegia (PEO) and are also associated with several mitochondrial depletion syndromes. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Molekulargewicht: 77.154 kDa

Gen-ID: 56652

UniProt: Q96RR1