Calpain 6 Antikörper

Produktnummer ABIN6290227

Produktdetails anti-Calpain 6 Antikörper

Target: Calpain 6 (CAPN6)

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Calpain 6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of human CAPN6

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000

Kommentare:

Expressed only in placenta

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20C. Avoid freeze / thaw cycles.

Details zu Calpain 6

Target: Calpain 6 (CAPN6)

Andere Bezeichnung: CAPN6 (CAPN6 Produkte)

Synonyme: CAPN6 antikoerper, CANPX antikoerper, CAPNX antikoerper, CalpM antikoerper, DJ914P14.1 antikoerper, calpain 6 antikoerper, CAPN6 antikoerper, Capn6 antikoerper

Hintergrund: Calpains are ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large subunit possesses a cysteine protease domain, and both subunits possess calcium-binding domains. Calpains have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. The protein encoded by this gene is highly expressed in the placenta. Its C-terminal region lacks any homology to the calmodulin-like domain of other calpains. The protein lacks critical active site residues and thus is suggested to be proteolytically inactive. The protein may play a role in tumor formation by inhibiting apoptosis and promoting angiogenesis.

Molekulargewicht: 74.576 kDa

Gen-ID: 827

UniProt: Q9Y6Q1