GDF5 Antikörper
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- Target Alle GDF5 Antikörper anzeigen
- GDF5 (Growth Differentiation Factor 5 (GDF5))
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Reaktivität
- Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser GDF5 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Aufreinigung
- Affinity purification
- Immunogen
- A synthetic peptide of human GDF5
- Isotyp
- IgG
- Top Product
- Discover our top product GDF5 Primärantikörper
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- Applikationshinweise
- WB 1:500 - 1:2000
- Kommentare
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Predominantly expressed in long bones during embryonic development, Expressed in monocytes (at protein level)
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20C. Avoid freeze / thaw cycles.
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- Target
- GDF5 (Growth Differentiation Factor 5 (GDF5))
- Andere Bezeichnung
- GDF5 (GDF5 Produkte)
- Synonyme
- CDMP1 antikoerper, gdf antikoerper, gdf-5 antikoerper, GDF5 antikoerper, BDA1C antikoerper, BMP14 antikoerper, LAP4 antikoerper, OS5 antikoerper, SYM1B antikoerper, SYNS2 antikoerper, Cdmp-1 antikoerper, bp antikoerper, brp antikoerper, Cdmp1 antikoerper, growth differentiation factor 5 L homeolog antikoerper, growth differentiation factor 5 antikoerper, gdf5.L antikoerper, GDF5 antikoerper, Gdf5 antikoerper
- Hintergrund
- This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates the development of numerous tissue and cell types, including cartilage, joints, brown fat, teeth, and the growth of neuronal axons and dendrites. Mutations in this gene are associated with acromesomelic dysplasia, brachydactyly, chondrodysplasia, multiple synostoses syndrome, proximal symphalangism, and susceptibility to osteoarthritis.
- Molekulargewicht
- 55.411 kDa
- Gen-ID
- 8200
- UniProt
- P43026
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