ADNP Antikörper (N-Term)

Produktnummer ABIN6287768

Produktdetails anti-ADNP Antikörper

Target: ADNP (Activity-Dependent Neuroprotector Homeobox (ADNP))

Bindungsspezifität: AA 80-160, N-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ADNP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Verwendungszweck: ADNP is a protein encoded by the ADNP gene which is approximately 123,5 kDa. It is a protein that is upregulated by vasoactive intestinal peptide and may be involved in its stimulatory effect on certain tumor cells. The encoded protein contains one homeobox and nine zinc finger domains, suggesting that it functions as a transcription factor. It may also increase the viability of certain cell types through modulation of p53 activity. ADNP is widely expressed with strong expression in heart, skeletal muscle, kidney and placenta. Mutations in the ADNP gene may result in Helsmoortel-van der Aa syndrome. STJ91502 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of ADNP protein.

Spezifität: ADNP Polyclonal Antibody detects endogenous levels of ADNP protein.

Produktmerkmale: Rabbit polyclonal to ADNP.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human ADNP

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:5000

Kommentare:

Widely expressed. Strong expression in heart, skeletal muscle, kidney and placenta. In brain, expression is stronger in the cerebellum and cortex regions. No expression detected in the colon. Strong increase of expression in colon and breast cancer tissues.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C, and avoid repeat freeze-thaw cycles.

Details zu ADNP

Target: ADNP (Activity-Dependent Neuroprotector Homeobox (ADNP))

Andere Bezeichnung: ADNP (ADNP Produkte)

Synonyme: AA589558 antikoerper, mKIAA0784 antikoerper, ADNP1 antikoerper, activity-dependent neuroprotective protein antikoerper, activity dependent neuroprotector homeobox antikoerper, activity-dependent neuroprotector homeobox antikoerper, Adnp antikoerper, ADNP antikoerper

Molekulargewicht: 124 kDa

Gen-ID: 23394

UniProt: Q9H2P0

Pathways: Regulation of Cell Size, Regulation of Carbohydrate Metabolic Process