Versican Antikörper (N-Term)
-
- Target Alle Versican (Vcan) Antikörper anzeigen
- Versican (Vcan)
-
Bindungsspezifität
- AA 510-590, N-Term
-
Reaktivität
- Human
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser Versican Antikörper ist unkonjugiert
-
Applikation
- ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Verwendungszweck
- Versican is a protein encoded by the VCAN gene which is approximately 372,8 kDa. Versican is secreted into the extracellular space. It is involved in the integrin pathway, ERK signalling, glycosaminoglycan metabolism and phospholipase-C pathway. This protein falls under the aggrecan/versican proteoglycan family. It is a large chondroitin sulfate proteoglycan and is a major component of the extracellular matrix. This protein is involved in cell adhesion, proliferation, migration and angiogenesis and plays a central role in tissue morphogenesis and maintenance. Versican is expressed in the cerebral white matter and plasma. Mutations in the VCAN gene may result in wagner vitreoretinopathy. STJ96239 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of versican protein.
- Spezifität
- Versican Polyclonal Antibody detects endogenous levels of Versican protein.
- Produktmerkmale
- Rabbit polyclonal to Versican.
- Aufreinigung
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Immunogen
- Synthesized peptide derived from human Versican
- Isotyp
- IgG
- Top Product
- Discover our top product Vcan Primärantikörper
-
-
- Applikationshinweise
-
IHC 1:100-1:300
ELISA 1:10000 - Kommentare
-
Cerebral white matter and plasma. Isoform V0 and isoform V1 are expressed in normal brain, gliomas, medulloblastomas, schwannomas, neurofibromas, and meningiomas. Isoform V2 is restricted to normal brain and gliomas. Isoform V3 is found in all these tissues except medulloblastomas.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C, and avoid repeat freeze-thaw cycles.
-
- Target
- Versican (Vcan)
- Andere Bezeichnung
- Versican (Vcan Produkte)
- Synonyme
- br146 antikoerper, cspg2 antikoerper, cspg2a antikoerper, sb:cb63 antikoerper, versican antikoerper, CSPG2 antikoerper, Cspg2 antikoerper, wgn antikoerper, ervr antikoerper, pg-m antikoerper, wgn1 antikoerper, Xversican antikoerper, dcan antikoerper, cspg2b antikoerper, fb99b07 antikoerper, wu:fb99b07 antikoerper, ERVR antikoerper, GHAP antikoerper, PG-M antikoerper, WGN antikoerper, WGN1 antikoerper, 5430420N07Rik antikoerper, 9430051N09 antikoerper, DPEAAE antikoerper, NG2 antikoerper, PG-M(V0) antikoerper, PG-M(V1) antikoerper, hdf antikoerper, versican a antikoerper, versican antikoerper, versican b antikoerper, vcana antikoerper, VCAN antikoerper, Vcan antikoerper, vcan antikoerper, vcanb antikoerper
- Molekulargewicht
- 372.82 kDa
- Gen-ID
- 1462
- UniProt
- P13611
- Pathways
- Glycosaminoglycan Metabolic Process
-