EGR2 Antikörper (C-Term)

Produktnummer ABIN6286258

Produktdetails anti-EGR2 Antikörper

Target: EGR2 (Early Growth Response 2 (EGR2))

Bindungsspezifität: AA 340-420, C-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EGR2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Verwendungszweck: Egr-2 is a protein encoded by the EGR2 gene which is approximately 50,3 kDa. Egr-2 is localised to the nucleus and is involved in toll-like receptor signalling pathway, HTLV-I infection, viral carcinogenesis and developmental biology. It is a sequence-specific DNA-binding transcription factor, it binds to two specific DNA sites located in the promoter region of HOXA4. It is also an E3 SUMO-protein ligase, helping SUMO1 conjugate to its coregulators NAB1 and NAB2, whose sumoylation down-regulates EGR2 own transcriptional activity. Egr-2 is expressed in the cells of the nervous system. Mutations in the EGR2 gene may result in congenital hypomyelinatingand Charcot-Marie-tooth disease. STJ92863 was purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. This antibody binds to endogenous Egr-2.

Spezifität: Egr-2 Polyclonal Antibody detects endogenous levels of Egr-2 protein.

Produktmerkmale: Rabbit polyclonal to Egr-2.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human Egr-2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000
IHC 1:100-1:300
IF 1:200-1:1000
ELISA 1:20000

Kommentare:

Detected in neutrophils (at protein level).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C, and avoid repeat freeze-thaw cycles.

Details zu EGR2

Target: EGR2 (Early Growth Response 2 (EGR2))

Andere Bezeichnung: Egr-2 (EGR2 Produkte)

Synonyme: AT591 antikoerper, CMT1D antikoerper, CMT4E antikoerper, KROX20 antikoerper, Egr-2 antikoerper, Krox-20 antikoerper, Krox20 antikoerper, NGF1-B antikoerper, Zfp-25 antikoerper, Zfp-6 antikoerper, KRX-20 antikoerper, cb427 antikoerper, egr2 antikoerper, id:ibd5073 antikoerper, krox20 antikoerper, krx20 antikoerper, wu:fb71h10 antikoerper, zgc:92210 antikoerper, frb35 antikoerper, early growth response 2 antikoerper, early growth response 2b antikoerper, early growth response 2a antikoerper, EGR2 antikoerper, Egr2 antikoerper, egr2b antikoerper, egr2a antikoerper

Molekulargewicht: 50 kDa

Gen-ID: 1958

UniProt: P18146