TLN1 Antikörper (C-Term)

Produktnummer ABIN6285636

Produktdetails anti-TLN1 Antikörper

Target: TLN1 (Talin 1 (TLN1))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TLN1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Verwendungszweck: Talin-1 is a protein encoded by the TLN1 gene which is approximately 269,2 kDa. Talin-1 is localised to the cytoplasm and cell surface. It is involved in RET signalling, integrin alphaIIb beta3 signalling, response to elevated platelet cytosolic Ca2+ and focal adhesion. It plays a significant role in the assembly of actin filaments and in spreading and migration of various cell types, including fibroblasts and osteoclasts. It co-distributes with integrins in the cell surface membrane in order to assist in the attachment of lymphocytes to other cells and attachment of adherent cells to extracellular matrices. Talin-1 is expressed in the blood, nervous system, liver, intestine and skin. Mutations in the TLN1 gene result in ovarian serous carcinoma. STJ97271 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of Talin-1 protein.

Spezifität: Talin-1 Polyclonal Antibody detects endogenous levels of Talin-1 protein.

Produktmerkmale: Rabbit polyclonal to Talin-1.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human Talin-1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000
IHC-P 1:100-1:300
ELISA 1:10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C, and avoid repeat freeze-thaw cycles.

Details zu TLN1

Target: TLN1 (Talin 1 (TLN1))

Andere Bezeichnung: Talin-1 (TLN1 Produkte)

Synonyme: ILWEQ antikoerper, TLN antikoerper, Tln antikoerper, sb:cb854 antikoerper, wu:fb05c02 antikoerper, TLN1 antikoerper, talin-1 antikoerper, tln antikoerper, talin 1 antikoerper, talin 1 L homeolog antikoerper, Talin 1 antikoerper, talin-1 antikoerper, TLN1 antikoerper, Tln1 antikoerper, tln1 antikoerper, tln1.L antikoerper, Bm1_56490 antikoerper, LOC100380665 antikoerper

Gen-ID: 7094

UniProt: Q9Y490

Pathways: Cell-Cell Junction Organization, ER-Nucleus Signaling, Maintenance of Protein Location