NOS2 Antikörper (AA 90-170)

Produktnummer ABIN6285268

Produktdetails anti-NOS2 Antikörper

Target: NOS2 (Nitric Oxide Synthase 2, Inducible (NOS2))

Bindungsspezifität: AA 90-170

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NOS2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Verwendungszweck: NOS2 is a protein encoded by the NOS2 gene which is approximately 131,1 kDa. NOS2 is localised to the cytoplasm. It is involved in arginine biosynthesis, toxoplasmosis, G-beta gamma signalling and PEDF induced signalling. It is a nitric oxide synthase messenger molecule with diverse functions throughout the body. In macrophages, it mediates tumoricidal and bactericidal actions and is also involved in inflammation by enhancing the synthesis of proinflammatory mediators such as IL6 and IL8. NOS2 is expressed in the liver, retina, bone cells and airway epithelial cells of the lung. Mutations in the NOS2 gene may result in borderline leprosy and Peyronie's disease. STJ94534 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of NOS2 protein.

Spezifität: NOS2 Polyclonal Antibody detects endogenous levels of NOS2 protein.

Produktmerkmale: Rabbit polyclonal to NOS2.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human NOS2 around the non-phosphorylation site of Y151.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000
ELISA 1:10000

Kommentare:

Expressed in the liver, retina, bone cells and airway epithelial cells of the lung. Not expressed in the platelets.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C, and avoid repeat freeze-thaw cycles.

Details zu NOS2

Target: NOS2 (Nitric Oxide Synthase 2, Inducible (NOS2))

Andere Bezeichnung: NOS2 (NOS2 Produkte)

Synonyme: HEP-NOS antikoerper, INOS antikoerper, NOS antikoerper, NOS2A antikoerper, NOS-II antikoerper, Nos-2 antikoerper, Nos2a antikoerper, i-NOS antikoerper, iNOS antikoerper, iNos antikoerper, NOS2a antikoerper, NOS2 antikoerper, BmNOS2 antikoerper, Nsl antikoerper, nos2 antikoerper, nitric oxide synthase 2 antikoerper, nitric oxide synthase 2, inducible antikoerper, inducible nitric oxide synthase antikoerper, inducible nitric-oxide synthase antikoerper, nanos C2HC-type zinc finger 2 antikoerper, NOS2 antikoerper, Nos2 antikoerper, nos2 antikoerper, LOC396821 antikoerper, NANOS2 antikoerper

Molekulargewicht: 131 kDa

Gen-ID: 4843

UniProt: P35228

Pathways: Retinoic Acid Receptor Signaling Pathway, Cellular Response to Molecule of Bacterial Origin, Inositol Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process