BMP2 Antikörper (C-Term)

Produktnummer ABIN6283442

Produktdetails anti-BMP2 Antikörper

Target: BMP2 (Bone Morphogenetic Protein 2 (BMP2))

Bindungsspezifität: AA 341-390, C-Term

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BMP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Verwendungszweck: BMP-2 is a protein encoded by the BMP2 gene which is approximately 44,7 kDa. BMP-2 is secreted into the extracellular space. It is involved in apoptotic pathways, PEDF induced signalling, the GPCR pathway and ERK signalling. This protein is a secreted ligand of the TGF-beta superfamily of proteins. It binds various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. It is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which plays a role in bone and cartilage development. BMP-2 is expressed in the bone, muscle, bone marrow, nervous system and lung. Mutations in the BMP2 gene may result in Cauda Equina syndrome. STJ97346 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of BMP-2 protein.

Spezifität: BMP-2 Polyclonal Antibody detects endogenous levels of BMP-2 protein.

Produktmerkmale: Rabbit polyclonal to BMP-2.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human BMP-2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000
IHC-P 1:100-1:300
ELISA 1:10000

Kommentare:

Particularly abundant in lung, spleen and colon and in low but significant levels in heart, brain, placenta, liver, skeletal muscle, kidney, pancreas, prostate, ovary and small intestine.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C, and avoid repeat freeze-thaw cycles.

Details zu BMP2

Target: BMP2 (Bone Morphogenetic Protein 2 (BMP2))

Andere Bezeichnung: BMP-2 (BMP2 Produkte)

Synonyme: BDA2 antikoerper, BMP2A antikoerper, AI467020 antikoerper, Bmp2a antikoerper, BMP-2 antikoerper, xBMP-2 antikoerper, xbmp2 antikoerper, BMP2 antikoerper, bmp2a antikoerper, bmp2 antikoerper, wu:fc59d09 antikoerper, bone morphogenetic protein 2 antikoerper, bone morphogenetic protein 2 L homeolog antikoerper, Bone morphogenetic protein 2 antikoerper, bone morphogenetic protein 2a antikoerper, BMP2 antikoerper, Bmp2 antikoerper, bmp2.L antikoerper, bmp2 antikoerper, bmp2a antikoerper

Gen-ID: 650

UniProt: P12643

Pathways: Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Regulation of Muscle Cell Differentiation, Growth Factor Binding, Positive Regulation of fat Cell Differentiation