Cytokeratin 19 Antikörper (Internal Region)
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- Target Alle Cytokeratin 19 (KRT19) Antikörper anzeigen
- Cytokeratin 19 (KRT19) (Keratin 19 (KRT19))
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Bindungsspezifität
- AA 200-280, Internal Region
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Cytokeratin 19 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Verwendungszweck
- Cytokeratin 19 is a protein encoded by the KRT19 gene which is approximately 44,1 kDa. Cytokeratin 19 is localised to the cytosol. It is involved in cytoskeletal signalling, developmental biology and keratinization. This protein falls under the keratin family and consists of acidic proteins which are arranged in pairs of heterotypic keratin chains. It plays a role in the organization of myofibers and together with KRT8, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle. Cytokeratin 19 is expressed in basal keratinocytes in the deep outer root sheath of hair follicles. Mutations in the KRT19 gene may result in lung cancer and thyroid cancer. STJ92634 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of Cytokeratin 19 protein.
- Spezifität
- Cytokeratin 19 Polyclonal Antibody detects endogenous levels of Cytokeratin 19 protein.
- Produktmerkmale
- Rabbit polyclonal to Cytokeratin 19.
- Aufreinigung
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Immunogen
- Synthesized peptide derived from human Cytokeratin 19
- Isotyp
- IgG
- Top Product
- Discover our top product KRT19 Primärantikörper
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- Applikationshinweise
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WB 1:500-1:2000
IHC 1:100-1:300
IF 1:200-1:1000
ELISA 1:10000 - Kommentare
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Expressed in a defined zone of basal keratinocytes in the deep outer root sheath of hair follicles. Also observed in sweat gland and mammary gland ductal and secretory cells, bile ducts, gastrointestinal tract, bladder urothelium, oral epithelia, esophagus, ectocervical epithelium (at protein level). Expressed in epidermal basal cells, in nipple epidermis and a defined region of the hair follicle. Also seen in a subset of vascular wall cells in both the veins and artery of human umbilical cord, and in umbilical cord vascular smooth muscle. Observed in muscle fibers accumulating in the costameres of myoplasm at the sarcolemma in structures that contain dystrophin and spectrin.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C, and avoid repeat freeze-thaw cycles.
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- Target
- Cytokeratin 19 (KRT19) (Keratin 19 (KRT19))
- Andere Bezeichnung
- Cytokeratin 19 (KRT19 Produkte)
- Synonyme
- CK19 antikoerper, K19 antikoerper, K1CS antikoerper, AI663979 antikoerper, EndoC antikoerper, Krt-1.19 antikoerper, Krt1-19 antikoerper, Ka19 antikoerper, k19 antikoerper, ck19 antikoerper, k1cs antikoerper, krt9 antikoerper, krt15 antikoerper, MGC76282 antikoerper, GK-19 antikoerper, MGC83069 antikoerper, KRT19 antikoerper, keratin 19 antikoerper, keratin 19 L homeolog antikoerper, keratin, type I cytoskeletal 19 antikoerper, KRT19 antikoerper, Krt19 antikoerper, krt19 antikoerper, krt19.L antikoerper, LOC100344434 antikoerper, LOC101117946 antikoerper
- Molekulargewicht
- 45 kDa
- Gen-ID
- 3880
- UniProt
- P08727
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