CMKLR1 Antikörper (Internal Region)

Produktnummer ABIN6281934

Produktdetails anti-CMKLR1 Antikörper

Target: CMKLR1 (Chemokine-Like Receptor 1 (CMKLR1))

Bindungsspezifität: AA 190-270, Internal Region

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CMKLR1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Verwendungszweck: ChemR23 is a protein encoded by the CMKLR1 gene which is approximately 42,3 kDa. ChemR23 is localised to the cell membrane. It is involved in the peptide ligand-binding receptors and is a receptor for the chemo-attractant adipokine chemerin/RARRES2 and for the omega-3 fatty acid derived molecule resolvin E1. Interaction with RARRES2 also induces activation of intracellular signalling molecules. ChemR23 is prominently expressed in developing osseous and cartilaginous tissue. Mutations in the CMKLR1 gene may result in Cataract and Alzheimer's disease. STJ92262 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of ChemR23 protein.

Spezifität: ChemR23 Polyclonal Antibody detects endogenous levels of ChemR23 protein.

Produktmerkmale: Rabbit polyclonal to ChemR23.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human ChemR23

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000
IHC 1:100-1:300
IF 1:200-1:1000
ELISA 1:20000

Kommentare:

Prominently expressed in developing osseous and cartilaginous tissue. Also found in adult parathyroid glands. Expressed in cardiovascular system, brain, kidney, gastrointestinal tissues and myeloid tissues. Expressed in a broad array of tissues associated with hematopoietic and immune function including, spleen, thymus, appendix, lymph node, bone marrow and fetal liver. Among leukocyte populations abundant expression in monocyte-derived macrophage and immature dendritic cells (DCs). High expression in blood monocytes and low levels in polymorphonuclear cells and T-cells. Expressed on endothelial cells. Highly expressed in differentiating adipocytes.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C, and avoid repeat freeze-thaw cycles.

Details zu CMKLR1

Target: CMKLR1 (Chemokine-Like Receptor 1 (CMKLR1))

Andere Bezeichnung: ChemR23 (CMKLR1 Produkte)

Synonyme: CHEMERINR antikoerper, ChemR23 antikoerper, DEZ antikoerper, RVER1 antikoerper, Gpcr27 antikoerper, mcmklr1 antikoerper, si:ch211-240b21.3 antikoerper, CMLKR1 antikoerper, Cmklr-1 antikoerper, GPCR antikoerper, chemerin chemokine-like receptor 1 antikoerper, chemokine-like receptor 1 antikoerper, CMKLR1 antikoerper, Cmklr1 antikoerper, cmklr1 antikoerper

Molekulargewicht: 42 kDa

Gen-ID: 1240

UniProt: Q99788