GPR18 Antikörper (Internal Region)

Produktnummer ABIN6281575

Produktdetails anti-GPR18 Antikörper

Target: GPR18 (G Protein-Coupled Receptor 18 (GPR18))

Bindungsspezifität: AA 160-240, Internal Region

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GPR18 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Verwendungszweck: GPR18 is a protein encoded by the GPR18 gene which is approximately 38,1 kDa. GPR18 is localised to the cell membrane. It is involved in peptide ligand-binding receptors and signalling by GPCR. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. It may contribute to the regulation of the immune system and plays a role in hypotensive responses, mediating reduction in intraocular and blood pressure. GPR18 is most abundant in the testis and spleen. STJ93370 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of GPR18 protein.

Spezifität: GPR18 Polyclonal Antibody detects endogenous levels of GPR18 protein.

Produktmerkmale: Rabbit polyclonal to GPR18.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human GPR18

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000
IHC 1:100-1:300
IF 1:200-1:1000
ELISA 1:5000

Kommentare:

Expressed in midpiece of spermatozoon (at protein level) . Most abundant in testis and spleen . Highly expressed in CD4 and CD8-positive T-cells as well as CD19-positive B-cells .

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C, and avoid repeat freeze-thaw cycles.

Details zu GPR18

Target: GPR18 (G Protein-Coupled Receptor 18 (GPR18))

Andere Bezeichnung: GPR18 (GPR18 Produkte)

Synonyme: GPR18 antikoerper, G protein-coupled receptor 18 antikoerper, GPR18 antikoerper, Gpr18 antikoerper

Molekulargewicht: 34 kDa

Gen-ID: 2841

UniProt: Q14330