CD63 Antikörper (Internal Region)
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- Target Alle CD63 Antikörper anzeigen
- CD63
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Bindungsspezifität
- AA 121-170, Internal Region
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser CD63 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Verwendungszweck
- CD63 is a protein encoded by the CD63 gene which is approximately 25,6 kDa. CD63 is localised to the cell membrane. It is involved in response to elevated platelet cytosolic Ca2+, the innate immune system and adhesion. This protein falls under the tetraspanin family. Most of these members are characterized by the presence of four hydrophobic domains. It is a cell surface glycoprotein that is known to complex with integrins and may function as a blood platelet activation marker. It also mediates signal transduction events that play a role in the regulation of cell development, activation, growth and motility. CD63 is expressed in skin, lung, blood, liver and muscle. Mutations in the CD63 gene may result in mast cell disease. STJ96890 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of CD63 protein.
- Spezifität
- CD63 Polyclonal Antibody detects endogenous levels of CD63 protein.
- Produktmerkmale
- Rabbit polyclonal to CD63.
- Aufreinigung
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Immunogen
- Synthesized peptide derived from human CD63.
- Isotyp
- IgG
- Top Product
- Discover our top product CD63 Primärantikörper
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- Applikationshinweise
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WB 1:500-1:2000
IHC-P 1:100-1:300
ELISA 1:20000 - Kommentare
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Detected in platelets (at protein level). Dysplastic nevi, radial growth phase primary melanomas, hematopoietic cells, tissue macrophages.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C, and avoid repeat freeze-thaw cycles.
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- Target
- CD63
- Andere Bezeichnung
- CD63 (CD63 Produkte)
- Synonyme
- C75951 antikoerper, ME491 antikoerper, Tspan30 antikoerper, LAMP-3 antikoerper, MLA1 antikoerper, OMA81H antikoerper, TSPAN30 antikoerper, TSP29FA antikoerper, CD63 antigen antikoerper, CD63 molecule antikoerper, Cd63 molecule antikoerper, Cd63 antikoerper, CD63 antikoerper
- Gen-ID
- 967
- UniProt
- P08962
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