WRAP53 Antikörper (Internal Region)

Produktnummer ABIN6266051

Produktdetails anti-WRAP53 Antikörper

Target: WRAP53 (WD Repeat Containing, Antisense To TP53 (WRAP53))

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser WRAP53 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Spezifität: WRAP53 Antibody detects endogenous levels of total WRAP53.

Homologie: Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Xenopus

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human WRAP53, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC 1:50-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu WRAP53

Target: WRAP53 (WD Repeat Containing, Antisense To TP53 (WRAP53))

Andere Bezeichnung: WRAP53 (WRAP53 Produkte)

Synonyme: DKCB3 antikoerper, TCAB1 antikoerper, WDR79 antikoerper, Wdr79 antikoerper, BC021790 antikoerper, WD repeat containing antisense to TP53 antikoerper, WD repeat containing, antisense to TP53 antikoerper, WD repeat containing, antisense to Trp53 antikoerper, WRAP53 antikoerper, Wrap53 antikoerper

Hintergrund:

Description: Essential component of the telomerase holoenzyme complex, a ribonucleoprotein complex essential for the replication of chromosome termini that elongates telomeres in most eukaryotes. In the telomerase holoenzyme complex, it controls telomerase localization to Cajal body. Required for delivery of TERC to telomeres during S phase and for telomerase activity. Binds small Cajal body RNAs (scaRNAs). The mRNA encoding this protein plays a critical role in the regulation of p53 expression at the post-transcriptional level, it is involved both in maintaining basal p53 mRNA levels and in p53 induction upon DNA damage.

Gene: WRAP53

Molekulargewicht: 72-75 kDa

Gen-ID: 55135

UniProt: Q9BUR4

Pathways: Telomere Maintenance