TSHZ3 Antikörper (Internal Region)

Produktnummer ABIN6265771

Produktdetails anti-TSHZ3 Antikörper

Target: TSHZ3 (ZNF537) (Zinc Finger Protein 537 (ZNF537))

Bindungsspezifität: Internal Region

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TSHZ3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Spezifität: TSH3 Antibody detects endogenous levels of total TSH3.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human TSH3, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu TSHZ3

Target: TSHZ3 (ZNF537) (Zinc Finger Protein 537 (ZNF537))

Andere Bezeichnung: TSHZ3 (ZNF537 Produkte)

Synonyme: ZNF537 antikoerper, A630038G13Rik antikoerper, Tsh3 antikoerper, Zfp537 antikoerper, mKIAA1474 antikoerper, teashirt3 antikoerper, TSH3 antikoerper, teashirt zinc finger homeobox 3 antikoerper, teashirt zinc finger family member 3 antikoerper, TSHZ3 antikoerper, Tshz3 antikoerper

Hintergrund:

Description: Transcriptional regulator involved in developmental processes. Function in association with APBB1, SET and HDAC factors as a transcriptional repressor, that inhibits the expression of CASP4. TSHZ3-mediated transcription repression involves the recruitment of histone deacetylases HDAC1 and HDAC2. Associates with chromatin in a region surrounding the CASP4 transcriptional start site(s) (PubMed:19343227). Regulates the development of neurons involved in both respiratory rhythm and airflow control. Promotes maintenance of nucleus ambiguus (nA) motoneurons, which govern upper airway function, and establishes a respiratory rhythm generator (RRG) activity compatible with survival at birth. Involved in the differentiation of the proximal uretic smooth muscle cells during developmental processes. Involved in the up-regulation of myocardin, that directs the expression of smooth muscle cells in the proximal ureter (By similarity). Involved in the modulation of glutamatergic synaptic transmission and long-term synaptic potentiation (By similarity).

Gene: TSHZ3

Molekulargewicht: 119 kDa

Gen-ID: 57616

UniProt: Q63HK5

Pathways: Regulation of Muscle Cell Differentiation