TSC22D3 Antikörper (Internal Region)
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- Target Alle TSC22D3 Antikörper anzeigen
- TSC22D3 (TSC22 Domain Family, Member 3 (TSC22D3))
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Bindungsspezifität
- Internal Region
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser TSC22D3 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA
- Spezifität
- TSC-22R Antibody detects endogenous levels of total TSC-22R.
- Homologie
- Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human TSC-22R, corresponding to a region within the internal amino acids.
- Isotyp
- IgG
- Top Product
- Discover our top product TSC22D3 Primärantikörper
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- Applikationshinweise
- WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
- Haltbarkeit
- 12 months
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- Target
- TSC22D3 (TSC22 Domain Family, Member 3 (TSC22D3))
- Andere Bezeichnung
- TSC22D3 (TSC22D3 Produkte)
- Synonyme
- dsipi antikoerper, MGC53285 antikoerper, zgc:65831 antikoerper, zgc:77028 antikoerper, TSC22D3 antikoerper, GILZ antikoerper, gilz antikoerper, tsc-22r antikoerper, DIP antikoerper, DSIPI antikoerper, TSC-22R antikoerper, hDIP antikoerper, Dsip1 antikoerper, Gilz antikoerper, Tilz3 antikoerper, Dsipi antikoerper, DSIP antikoerper, TSC22 domain family member 3 L homeolog antikoerper, TSC22 domain family, member 3 antikoerper, TSC22 domain family member 3 antikoerper, tsc22d3.L antikoerper, tsc22d3 antikoerper, TSC22D3 antikoerper, Tsc22d3 antikoerper
- Hintergrund
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Description: Protects T-cells from IL2 deprivation-induced apoptosis through the inhibition of FOXO3A transcriptional activity that leads to the down-regulation of the pro-apoptotic factor BCL2L11. In macrophages, plays a role in the anti-inflammatory and immunosuppressive effects of glucocorticoids and IL10. In T-cells, inhibits anti-CD3-induced NFKB1 nuclear translocation. In vitro, suppresses AP1 and NFKB1 DNA-binding activities (By similarity). Isoform 1 inhibits myogenic differentiation and mediates anti-myogenic effects of glucocorticoids by binding and regulating MYOD1 and HDAC1 transcriptional activity resulting in reduced expression of MYOG (By similarity).
Gene: TSC22D3
- Molekulargewicht
- 15 kDa
- Gen-ID
- 1831
- UniProt
- Q99576
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