TFCP2L1 Antikörper (N-Term)

Produktnummer ABIN6265527

Produktdetails anti-TFCP2L1 Antikörper

Target: TFCP2L1 (Transcription Factor CP2-Like 1 (TFCP2L1))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TFCP2L1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Spezifität: TF2L1 Antibody detects endogenous levels of total TF2L1.

Homologie: Pig,Bovine,Sheep,Dog

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human TF2L1, corresponding to a region within N-terminal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-3000, IHC 1:200, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu TFCP2L1

Target: TFCP2L1 (Transcription Factor CP2-Like 1 (TFCP2L1))

Andere Bezeichnung: TFCP2L1 (TFCP2L1 Produkte)

Synonyme: CRTR1 antikoerper, LBP-9 antikoerper, LBP9 antikoerper, 1810030F05Rik antikoerper, 4932442M07Rik antikoerper, AA575098 antikoerper, Cp2l1 antikoerper, Crtr-1 antikoerper, D930018N21Rik antikoerper, Tcfcp2l1 antikoerper, zgc:91796 antikoerper, TFCP2L1 antikoerper, lbp-9 antikoerper, crtr1 antikoerper, lbp9 antikoerper, tfcp2l1 antikoerper, tfcp2l1a antikoerper, transcription factor CP2 like 1 antikoerper, transcription factor CP2-like protein 1 antikoerper, transcription factor CP2-like 1 antikoerper, transcription factor CP2-like 1 L homeolog antikoerper, TFCP2L1 antikoerper, LOC100078599 antikoerper, Tfcp2l1 antikoerper, tfcp2l1 antikoerper, tfcp2l1.L antikoerper

Hintergrund:

Description: Transcription factor that facilitates establishment and maintenance of pluripotency in embryonic stem cells (ESCs) (PubMed:25215486, PubMed:26906118). With KLF2, acts as the major effector of self-renewal that mediates induction of pluripotency downstream of LIF/STAT3 and Wnt/beta-catenin signaling (By similarity). Required for normal duct development in the salivary gland and kidney (By similarity). Coordinates the development of the kidney collecting ducts intercalated (IC) and principal (PC) cells, which regulate acid-base and salt-water homeostasis, respectively (By similarity). Regulates the expression of IC genes including subunits B1 and D2 of the V-ATPase complex, OXGR1, CA12, SLC4A1, AQP6 and IC-specific transcription factor FOXI1 (By similarity). Regulates also the expression of JAG1 and subsequent notch signaling in the collecting duct (By similarity). JAG1 initiates notch signaling in PCs but inhibits notch signaling in ICs (By similarity). Acts as a transcriptional suppressor that may suppress UBP1-mediated transcriptional activation (By similarity). Modulates the placental expression of CYP11A1 (PubMed:10644752).

Gene: TFCP2L1

Molekulargewicht: 55 kDa

Gen-ID: 29842

UniProt: Q9NZI6