SMYD2A Antikörper (Internal Region)
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- Target Alle SMYD2A Antikörper anzeigen
- SMYD2A (SET and MYND Domain Containing 2a (SMYD2A))
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Bindungsspezifität
- Internal Region
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser SMYD2A Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA
- Spezifität
- SMYD2 Antibody detects endogenous levels of total SMYD2.
- Homologie
- Pig,Bovine,Horse,Rabbit,Dog
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human SMYD2, corresponding to a region within the internal amino acids.
- Isotyp
- IgG
- Top Product
- Discover our top product SMYD2A Primärantikörper
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- Applikationshinweise
- WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
- Haltbarkeit
- 12 months
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- Target
- SMYD2A (SET and MYND Domain Containing 2a (SMYD2A))
- Andere Bezeichnung
- SMYD2 (SMYD2A Produkte)
- Synonyme
- HSKM-B antikoerper, KMT3C antikoerper, ZMYND14 antikoerper, 1110020E07Rik antikoerper, 4930402C15 antikoerper, Zmynd14 antikoerper, smyd2-a antikoerper, im:7146196 antikoerper, smyd2 antikoerper, wu:fc02f02 antikoerper, zgc:110553 antikoerper, si:dkey-121j17.3 antikoerper, zgc:136609 antikoerper, SET and MYND domain containing 2 antikoerper, SET and MYND domain containing 2 S homeolog antikoerper, SET and MYND domain containing 2a antikoerper, SET and MYND domain containing 2b antikoerper, SMYD2 antikoerper, Smyd2 antikoerper, smyd2.S antikoerper, smyd2a antikoerper, smyd2b antikoerper
- Hintergrund
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Description: Protein-lysine N-methyltransferase that methylates both histones and non-histone proteins, including p53/TP53 and RB1. Specifically methylates histone H3 'Lys-4' (H3K4me) and dimethylates histone H3 'Lys-36' (H3K36me2). Shows even higher methyltransferase activity on p53/TP53. Monomethylates 'Lys-370' of p53/TP53, leading to decreased DNA-binding activity and subsequent transcriptional regulation activity of p53/TP53. Monomethylates RB1 at 'Lys-860'.
Gene: SMYD2
- Molekulargewicht
- 49 kDa
- Gen-ID
- 56950
- UniProt
- Q9NRG4
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