SMYD2A Antikörper (Internal Region)

Produktnummer ABIN6265198

Produktdetails anti-SMYD2A Antikörper

Target: SMYD2A (SET and MYND Domain Containing 2a (SMYD2A))

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SMYD2A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Spezifität: SMYD2 Antibody detects endogenous levels of total SMYD2.

Homologie: Pig,Bovine,Horse,Rabbit,Dog

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human SMYD2, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu SMYD2A

Target: SMYD2A (SET and MYND Domain Containing 2a (SMYD2A))

Andere Bezeichnung: SMYD2 (SMYD2A Produkte)

Synonyme: HSKM-B antikoerper, KMT3C antikoerper, ZMYND14 antikoerper, 1110020E07Rik antikoerper, 4930402C15 antikoerper, Zmynd14 antikoerper, smyd2-a antikoerper, im:7146196 antikoerper, smyd2 antikoerper, wu:fc02f02 antikoerper, zgc:110553 antikoerper, si:dkey-121j17.3 antikoerper, zgc:136609 antikoerper, SET and MYND domain containing 2 antikoerper, SET and MYND domain containing 2 S homeolog antikoerper, SET and MYND domain containing 2a antikoerper, SET and MYND domain containing 2b antikoerper, SMYD2 antikoerper, Smyd2 antikoerper, smyd2.S antikoerper, smyd2a antikoerper, smyd2b antikoerper

Hintergrund:

Description: Protein-lysine N-methyltransferase that methylates both histones and non-histone proteins, including p53/TP53 and RB1. Specifically methylates histone H3 'Lys-4' (H3K4me) and dimethylates histone H3 'Lys-36' (H3K36me2). Shows even higher methyltransferase activity on p53/TP53. Monomethylates 'Lys-370' of p53/TP53, leading to decreased DNA-binding activity and subsequent transcriptional regulation activity of p53/TP53. Monomethylates RB1 at 'Lys-860'.

Gene: SMYD2

Molekulargewicht: 49 kDa

Gen-ID: 56950

UniProt: Q9NRG4