SLC1A1 Antikörper (C-Term)
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- Target Alle SLC1A1 Antikörper anzeigen
- SLC1A1 (Solute Carrier Family 1 (Neuronal/epithelial High Affinity Glutamate Transporter, System Xag), Member 1 (SLC1A1))
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Bindungsspezifität
- C-Term
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Reaktivität
- Human, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser SLC1A1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA
- Spezifität
- EAAT3 Antibody detects endogenous levels of total EAAT3.
- Homologie
- Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human EAAT3, corresponding to a region within C-terminal amino acids.
- Isotyp
- IgG
- Top Product
- Discover our top product SLC1A1 Primärantikörper
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- Applikationshinweise
- WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
- Haltbarkeit
- 12 months
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- Target
- SLC1A1 (Solute Carrier Family 1 (Neuronal/epithelial High Affinity Glutamate Transporter, System Xag), Member 1 (SLC1A1))
- Andere Bezeichnung
- SLC1A1 (SLC1A1 Produkte)
- Synonyme
- GB16911 antikoerper, EAAT3 antikoerper, SLC1A2a antikoerper, zgc:91959 antikoerper, EAAC1 antikoerper, SCZD18 antikoerper, D130048G10Rik antikoerper, EAAC2 antikoerper, MEAAC1 antikoerper, Eaac1 antikoerper, Eaat3 antikoerper, REAAC1 antikoerper, excitatory amino acid transporter 3 antikoerper, solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 antikoerper, solute carrier family 1 member 1 antikoerper, LOC412382 antikoerper, slc1a1 antikoerper, SLC1A1 antikoerper, CpipJ_CPIJ000674 antikoerper, CpipJ_CPIJ001134 antikoerper, Slc1a1 antikoerper
- Hintergrund
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Description: Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D-aspartate (PubMed:7914198, PubMed:7521911, PubMed:8857541, PubMed:26690923, PubMed:21123949). Can also transport L-cysteine (PubMed:21123949). Functions as a symporter that transports one amino acid molecule together with two or three Na+ ions and one proton, in parallel with the counter-transport of one K+ ion (PubMed:7521911, PubMed:8857541, PubMed:26690923). Mediates Cl- flux that is not coupled to amino acid transport, this avoids the accumulation of negative charges due to aspartate and Na+ symport (PubMed:8857541, PubMed:26690923). Plays an important role in L-glutamate and L-aspartate reabsorption in renal tubuli (PubMed:21123949). Plays a redundant role in the rapid removal of released glutamate from the synaptic cleft, which is essential for terminating the postsynaptic action of glutamate (By similarity). Negatively regulated by ARL6IP5 (By similarity).
Gene: SLC1A1
- Molekulargewicht
- 63 kDa
- Gen-ID
- 6505
- UniProt
- P43005
- Pathways
- Dicarboxylic Acid Transport
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