SENP3 Antikörper (Internal Region)

Produktnummer ABIN6264985

Produktdetails anti-SENP3 Antikörper

Target: SENP3 (SUMO/sentrin Specific Peptidase 3 (SENP3))

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SENP3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Spezifität: SENP3 Antibody detects endogenous levels of total SENP3.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human SENP3, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu SENP3

Target: SENP3 (SUMO/sentrin Specific Peptidase 3 (SENP3))

Andere Bezeichnung: SENP3 (SENP3 Produkte)

Synonyme: SMT3IP1 antikoerper, SSP3 antikoerper, Ulp1 antikoerper, AA408656 antikoerper, Smt3ip antikoerper, Smt3ip1 antikoerper, ssp3 antikoerper, smt3ip1 antikoerper, fa03d07 antikoerper, wu:fa03d07 antikoerper, senp3 antikoerper, SUMO1/sentrin/SMT3 specific peptidase 3 antikoerper, SUMO/sentrin specific peptidase 3 antikoerper, Sumo1/sentrin/SMT3 specific peptidase 3 antikoerper, SUMO1/sentrin/SMT3 specific peptidase 3b antikoerper, SUMO1/sentrin/SMT3 specific peptidase 3 L homeolog antikoerper, SENP3 antikoerper, Senp3 antikoerper, senp3 antikoerper, senp3b antikoerper, senp3.L antikoerper

Hintergrund:

Description: Protease that releases SUMO2 and SUMO3 monomers from sumoylated substrates, but has only weak activity against SUMO1 conjugates. Deconjugates SUMO2 from MEF2D, which increases its transcriptional activation capability. Deconjugates SUMO2 and SUMO3 from CDCA8. Redox sensor that, when redistributed into nucleoplasm, can act as an effector to enhance HIF1A transcriptional activity by desumoylating EP300. Required for rRNA processing through deconjugation of SUMO2 and SUMO3 from nucleophosmin, NPM1. Plays a role in the regulation of sumoylation status of ZNF148. Functions as a component of the Five Friends of Methylated CHTOP (5FMC) complex, the 5FMC complex is recruited to ZNF148 by methylated CHTOP, leading to desumoylation of ZNF148 and subsequent transactivation of ZNF148 target genes.

Gene: SENP3

Molekulargewicht: 65 kDa

Gen-ID: 26168

UniProt: Q9H4L4