SCN11A Antikörper (Internal Region)

Produktnummer ABIN6264942

Produktdetails anti-SCN11A Antikörper

Target: SCN11A (Sodium Channel, Voltage-Gated, Type XI, alpha Subunit (SCN11A))

Bindungsspezifität: Internal Region

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SCN11A Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Spezifität: SCN11A Antibody detects endogenous levels of total SCN11A.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human SCN11A, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-3000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu SCN11A

Target: SCN11A (Sodium Channel, Voltage-Gated, Type XI, alpha Subunit (SCN11A))

Andere Bezeichnung: SCN11A (SCN11A Produkte)

Synonyme: SCN11A antikoerper, NSS2 antikoerper, NaN antikoerper, NaT antikoerper, SNS2 antikoerper, NAV1.9 antikoerper, SCN12A antikoerper, SNS-2 antikoerper, sodium voltage-gated channel alpha subunit 11 antikoerper, sodium channel protein type 11 subunit alpha antikoerper, sodium channel, voltage-gated, type XI, alpha antikoerper, SCN11A antikoerper, LOC100349709 antikoerper, Scn11a antikoerper

Hintergrund:

Description: This protein mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which sodium ions may pass in accordance with their electrochemical gradient. It is a tetrodotoxin-resistant sodium channel isoform. Also involved, with the contribution of the receptor tyrosine kinase NTRK2, in rapid BDNF-evoked neuronal depolarization.

Gene: SCN11A

Molekulargewicht: 205 kDa

Gen-ID: 11280

UniProt: Q9UI33