RYR2 Antikörper (Internal Region)
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- Target Alle RYR2 Antikörper anzeigen
- RYR2 (Ryanodine Receptor 2 (Cardiac) (RYR2))
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Bindungsspezifität
- Internal Region
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser RYR2 Antikörper ist unkonjugiert
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Applikation
- Immunohistochemistry (IHC), Western Blotting (WB)
- Spezifität
- RYR2 Antibody detects endogenous levels of total RYR2.
- Homologie
- Pig,Bovine,Horse,Sheep,Rabbit
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human RYR2, corresponding to a region within the internal amino acids.
- Isotyp
- IgG
- Top Product
- Discover our top product RYR2 Primärantikörper
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- Applikationshinweise
- WB 1:500-1:2000, IHC 1:50-1:200
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol. .
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
- Haltbarkeit
- 12 months
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- Target
- RYR2 (Ryanodine Receptor 2 (Cardiac) (RYR2))
- Andere Bezeichnung
- RYR2 (RYR2 Produkte)
- Synonyme
- RYR2 antikoerper, ARVC2 antikoerper, ARVD2 antikoerper, RYR-2 antikoerper, RyR antikoerper, VTSIP antikoerper, 9330127I20Rik antikoerper, ryanodine receptor 2 antikoerper, ryanodine receptor 2, cardiac antikoerper, RYR2 antikoerper, Ryr2 antikoerper
- Hintergrund
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Description: Calcium channel that mediates the release of Ca2+ from the sarcoplasmic reticulum into the cytoplasm and thereby plays a key role in triggering cardiac muscle contraction. Aberrant channel activation can lead to cardiac arrhythmia. In cardiac myocytes, calcium release is triggered by increased Ca2+ levels due to activation of the L-type calcium channel CACNA1C. The calcium channel activity is modulated by formation of heterotetramers with RYR3. Required for cellular calcium ion homeostasis. Required for embryonic heart development.
Gene: RYR2
- Molekulargewicht
- 564 kDa
- Gen-ID
- 6262
- UniProt
- Q92736
- Pathways
- Myometrial Relaxation and Contraction
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