RQCD1 Antikörper (Internal Region)

Produktnummer ABIN6264862

Produktdetails anti-RQCD1 Antikörper

Target: RQCD1 (RCD1 Required For Cell Differentiation1 Homolog (RQCD1))

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RQCD1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Spezifität: RQCD1 Antibody detects endogenous levels of total RQCD1.

Homologie: Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human RQCD1, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC 1:50-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu RQCD1

Target: RQCD1 (RCD1 Required For Cell Differentiation1 Homolog (RQCD1))

Andere Bezeichnung: CNOT9 (RQCD1 Produkte)

Synonyme: 2610007F23Rik antikoerper, AI593551 antikoerper, Fl10 antikoerper, CNOT9 antikoerper, CT129 antikoerper, RCD-1 antikoerper, RCD1 antikoerper, wu:fb52b11 antikoerper, wu:fb74e08 antikoerper, zgc:85618 antikoerper, CCR4-NOT transcription complex, subunit 9 antikoerper, CCR4-NOT transcription complex subunit 9 antikoerper, Cnot9 antikoerper, CNOT9 antikoerper, cnot9 antikoerper

Hintergrund:

Description: Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Involved in down-regulation of MYB- and JUN-dependent transcription. May play a role in cell differentiation (By similarity). Can bind oligonucleotides, such as poly-G, poly-C or poly-T (in vitro), but the physiological relevance of this is not certain. Does not bind poly-A. Enhances ligand-dependent transcriptional activity of nuclear hormone receptors, including RARA, expect ESR1-mediated transcription that is not only slightly increased, if at all.

Gene: CNOT9

Molekulargewicht: 34-40 kDa

Gen-ID: 9125

UniProt: Q92600

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling