DLG4 Antikörper (C-Term)

Produktnummer ABIN6268831

Produktdetails anti-DLG4 Antikörper

Target: DLG4 (Discs, Large Homolog 4 (Drosophila) (DLG4))

Bindungsspezifität: C-Term

Reaktivität: Ratte, Maus, Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DLG4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Spezifität: PSD95 Antibody detects endogenous levels of total PSD95.

Homologie: Zebrafish,Bovine,Horse,Sheep,Rabbit

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human PSD95, corresponding to a region within C-terminal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu DLG4

Target: DLG4 (Discs, Large Homolog 4 (Drosophila) (DLG4))

Andere Bezeichnung: DLG4 (DLG4 Produkte)

Synonyme: 11 antikoerper, CG1725 antikoerper, CG1730 antikoerper, CPD antikoerper, DLG antikoerper, DLG-A antikoerper, Discs-large antikoerper, Dlg antikoerper, Dlg-A antikoerper, Dlg1 antikoerper, DlgA antikoerper, Dmel\\CG1725 antikoerper, Drodlg antikoerper, PSD95 antikoerper, SAP97 antikoerper, anon-EST:Posey93 antikoerper, anon-WO03040301.258 antikoerper, anon-WO03040301.260 antikoerper, anon-WO03040301.268 antikoerper, d. lg.-1 antikoerper, dlg antikoerper, dlg-1 antikoerper, dlg-A antikoerper, dlgA antikoerper, dlgS97 antikoerper, l(1)10Bf antikoerper, l(1)G0276 antikoerper, l(1)G0342 antikoerper, l(1)G0456 antikoerper, l(1)G19 antikoerper, l(1)L11 antikoerper, l(1)bwn antikoerper, l(1)d.lg-1 antikoerper, l(1)d.lg.-1 antikoerper, l(1)discs large antikoerper, l(1)dlg antikoerper, l(1)dlg-1 antikoerper, l(1)dlg1 antikoerper, l(1)l.pr.-2 antikoerper, l(1)lpr-2 antikoerper, misb antikoerper, dlgh4 antikoerper, psd95 antikoerper, sap90 antikoerper, sap-90 antikoerper, LLGL1 antikoerper, Dlgh4 antikoerper, PSD-95 antikoerper, SAP90 antikoerper, SAP90A antikoerper, Sap90 antikoerper, SAP-90 antikoerper, DLG4 antikoerper, discs large 1 antikoerper, discs, large homolog 4 antikoerper, discs large MAGUK scaffold protein 4 antikoerper, discs, large homolog 4b (Drosophila) antikoerper, discs, large homolog 4 (Drosophila) antikoerper, dlg1 antikoerper, dlg4 antikoerper, DLG4 antikoerper, dlg4b antikoerper, Dlg4 antikoerper

Hintergrund:

Description: Interacts with the cytoplasmic tail of NMDA receptor subunits and shaker-type potassium channels. Required for synaptic plasticity associated with NMDA receptor signaling. Overexpression or depletion of DLG4 changes the ratio of excitatory to inhibitory synapses in hippocampal neurons. May reduce the amplitude of ASIC3 acid-evoked currents by retaining the channel intracellularly. May regulate the intracellular trafficking of ADR1B. Also regulates AMPA-type glutamate receptor (AMPAR) immobilization at postsynaptic density keeping the channels in an activated state in the presence of glutamate and preventing synaptic depression.

Gene: DLG4

Molekulargewicht: 105 kDa

Gen-ID: 1742

UniProt: P78352

Pathways: Regulation of Muscle Cell Differentiation, Synaptic Membrane, Skeletal Muscle Fiber Development, Asymmetric Protein Localization, Regulation of long-term Neuronal Synaptic Plasticity