PIP4K2A Antikörper (Internal Region)

Produktnummer ABIN6264229

Produktdetails anti-PIP4K2A Antikörper

Target: PIP4K2A (Phosphatidylinositol-5-Phosphate 4-Kinase, Type II, alpha (PIP4K2A))

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PIP4K2A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Spezifität: PIP4K2A Antibody detects endogenous levels of total PIP4K2A.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human PIP4K2A, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu PIP4K2A

Target: PIP4K2A (Phosphatidylinositol-5-Phosphate 4-Kinase, Type II, alpha (PIP4K2A))

Andere Bezeichnung: PIP4K2A (PIP4K2A Produkte)

Synonyme: PI5P4KA antikoerper, PIP5K2A antikoerper, PIP5KII-alpha antikoerper, PIP5KIIA antikoerper, PIPK antikoerper, AW742916 antikoerper, Pip5k2a antikoerper, pipk antikoerper, pi5p4ka antikoerper, pip5k2a antikoerper, pip5kiia antikoerper, pip4k2a antikoerper, zgc:194746 antikoerper, zgc:194777 antikoerper, phosphatidylinositol-5-phosphate 4-kinase type 2 alpha antikoerper, phosphatidylinositol-5-phosphate 4-kinase, type II, alpha antikoerper, phosphatidylinositol-5-phosphate 4-kinase, type II, alpha S homeolog antikoerper, phosphatidylinositol-5-phosphate 4-kinase, type II, alpha a antikoerper, PIP4K2A antikoerper, Pip4k2a antikoerper, pip4k2a.S antikoerper, pip4k2a antikoerper, pip4k2aa antikoerper

Hintergrund:

Description: Catalyzes the phosphorylation of phosphatidylinositol 5-phosphate (PtdIns5P) on the fourth hydroxyl of the myo-inositol ring, to form phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). May exert its function by regulating the levels of PtdIns5P, which functions in the cytosol by increasing AKT activity and in the nucleus signals through ING2. May regulate the pool of cytosolic PtdIns5P in response to the activation of tyrosine phosphorylation. May negatively regulate insulin-stimulated glucose uptake by lowering the levels of PtdIns5P. May be involved in thrombopoiesis, and the terminal maturation of megakaryocytes and regulation of their size.

Gene: PIP4K2A

Molekulargewicht: 46 kDa

Gen-ID: 5305

UniProt: P48426

Pathways: Inositol Metabolic Process