LEPREL2 Antikörper (Internal Region)

Produktnummer ABIN6263960

Produktdetails anti-LEPREL2 Antikörper

Target: LEPREL2 (Leprecan Like Protein 2 (LEPREL2))

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LEPREL2 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Western Blotting (WB)

Spezifität: P3H3 Antibody detects endogenous levels of total P3H3.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human P3H3, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC 1:50-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu LEPREL2

Target: LEPREL2 (Leprecan Like Protein 2 (LEPREL2))

Andere Bezeichnung: P3H3 (LEPREL2 Produkte)

Synonyme: GRCB antikoerper, HSU47926 antikoerper, P3H3 antikoerper, BC016431 antikoerper, Grcb antikoerper, P3h3 antikoerper, prolyl 3-hydroxylase 3 antikoerper, P3H3 antikoerper, P3h3 antikoerper

Hintergrund:

Description: Part of a complex composed of PLOD1, P3H3 and P3H4 that catalyzes hydroxylation of lysine residues in collagen alpha chains and is required for normal assembly and cross-linkling of collagen fibrils. Required for normal hydroxylation of lysine residues in type I collagen chains in skin, bone, tendon, aorta and cornea. Required for normal skin stability via its role in hydroxylation of lysine residues in collagen alpha chains and in collagen fibril assembly. Apparently not required for normal prolyl 3-hydroxylation on collagen chains, possibly because it functions redundantly with other prolyl 3-hydroxylases.

Gene: P3H3

Molekulargewicht: 82 kDa

Gen-ID: 10536

UniProt: Q8IVL6