OMA1 Antikörper (Internal Region)

Produktnummer ABIN6263821

Produktdetails anti-OMA1 Antikörper

Target: OMA1 (OMA1 Zinc Metallopeptidase Homolog (OMA1))

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser OMA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Spezifität: OMA1 Antibody detects endogenous levels of total OMA1.

Homologie: Zebrafish,Bovine,Sheep,Rabbit

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human OMA1, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu OMA1

Target: OMA1 (OMA1 Zinc Metallopeptidase Homolog (OMA1))

Andere Bezeichnung: OMA1 (OMA1 Produkte)

Synonyme: 2010001O09Rik antikoerper, DAB1 antikoerper, MPRP-1 antikoerper, YKR087C antikoerper, ZMPOMA1 antikoerper, peptidase antikoerper, RGD1304821 antikoerper, oma1 antikoerper, OMA1 zinc metallopeptidase antikoerper, si:ch73-215a11.1 antikoerper, olfactory receptor 4K2 antikoerper, OMA1 antikoerper, Oma1 antikoerper, si:ch73-215a11.1 antikoerper, LOC531304 antikoerper

Hintergrund:

Description: Metalloprotease that is part of the quality control system in the inner membrane of mitochondria. Following stress conditions that induce loss of mitochondrial membrane potential, mediates cleavage of OPA1 at S1 position, leading to OPA1 inactivation and negative regulation of mitochondrial fusion. May also cleave UQCC3 under these conditions. Its role in mitochondrial quality control is essential for regulating lipid metabolism as well as to maintain body temperature and energy expenditure under cold-stress conditions.

Gene: OMA1

Molekulargewicht: 60 kDa

Gen-ID: 115209

UniProt: Q96E52