NUP62 Antikörper (Internal Region)

Produktnummer ABIN6263778

Produktdetails anti-NUP62 Antikörper

Target: NUP62 (Nucleoporin 62kDa (NUP62))

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NUP62 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Spezifität: NUP62 Antibody detects endogenous levels of total NUP62.

Homologie: Pig,Sheep,Dog,Chicken,Xenopus

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human NUP62, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu NUP62

Target: NUP62 (Nucleoporin 62kDa (NUP62))

Andere Bezeichnung: NUP62 (NUP62 Produkte)

Synonyme: IBSN antikoerper, SNDI antikoerper, p62 antikoerper, NUP62 antikoerper, AA589433 antikoerper, AI426861 antikoerper, AI790512 antikoerper, AU045898 antikoerper, D7Ertd649e antikoerper, Nupc1 antikoerper, CG6251 antikoerper, Dmel\\CG6251 antikoerper, DDBDRAFT_0167902 antikoerper, DDBDRAFT_0237712 antikoerper, DDB_0167902 antikoerper, DDB_0237712 antikoerper, nup62 antikoerper, Np62 antikoerper, nucleoporin 62 antikoerper, hypothetical protein antikoerper, nucleoporin 62kDa antikoerper, Nucleoporin 62kD antikoerper, predicted protein antikoerper, nuclear pore protein antikoerper, Nup62 nuclear pore complex glycoprotein p62-related protein (IC) antikoerper, Nuclear pore glycoprotein p62 antikoerper, NUP62 antikoerper, PGTG_03077 antikoerper, Nup62 antikoerper, nup62 antikoerper

Hintergrund:

Description: Essential component of the nuclear pore complex (PubMed:1915414). The N-terminal is probably involved in nucleocytoplasmic transport (PubMed:1915414). The C-terminal is involved in protein-protein interaction probably via coiled-coil formation, promotes its association with centrosomes and may function in anchorage of p62 to the pore complex (PubMed:1915414, PubMed:24107630). Plays a role in mitotic cell cycle progression by regulating centrosome segregation, centriole maturation and spindle orientation (PubMed:24107630). It might be involved in protein recruitment to the centrosome after nuclear breakdown (PubMed:24107630).

Gene: NUP62

Molekulargewicht: 53kDa

Gen-ID: 23636

UniProt: P37198

Pathways: EGFR Signaling Pathway, SARS-CoV-2 Protein Interaktom