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ZC3HC1 Antikörper (C-Term)

ZC3HC1 Reaktivität: Human WB, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6263640
  • Target Alle ZC3HC1 Antikörper anzeigen
    ZC3HC1 (Zinc Finger, C3HC-Type Containing 1 (ZC3HC1))
    Bindungsspezifität
    • 18
    • 15
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 47
    • 23
    • 20
    • 6
    Human
    Wirt
    • 47
    Kaninchen
    Klonalität
    • 47
    Polyklonal
    Konjugat
    • 19
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser ZC3HC1 Antikörper ist unkonjugiert
    Applikation
    • 31
    • 18
    • 13
    • 13
    • 10
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    Spezifität
    NIPA Antibody detects endogenous levels of total NIPA.
    Homologie
    Pig,Bovine,Horse,Sheep,Rabbit,Dog
    Aufreinigung
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human NIPA, corresponding to a region within C-terminal amino acids.
    Isotyp
    IgG
    Top Product
    Discover our top product ZC3HC1 Primärantikörper
  • Applikationshinweise
    WB 1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C. Stable for 12 months from date of receipt.
    Haltbarkeit
    12 months
  • Target
    ZC3HC1 (Zinc Finger, C3HC-Type Containing 1 (ZC3HC1))
    Andere Bezeichnung
    ZC3HC1 (ZC3HC1 Produkte)
    Synonyme
    1110054L24Rik antikoerper, AU018540 antikoerper, AU019789 antikoerper, HSPC216 antikoerper, Nipa antikoerper, NIPA antikoerper, RGD1561099 antikoerper, zinc finger, C3HC type 1 antikoerper, zinc finger C3HC-type containing 1 antikoerper, zinc finger, C3HC-type containing 1 antikoerper, Zc3hc1 antikoerper, ZC3HC1 antikoerper
    Hintergrund

    Description: Essential component of a SCF-type E3 ligase complex, SCF(NIPA), a complex that controls mitotic entry by mediating ubiquitination and subsequent degradation of cyclin B1 (CCNB1). Its cell-cycle-dependent phosphorylation regulates the assembly of the SCF(NIPA) complex, restricting CCNB1 ubiquitination activity to interphase. Its inactivation results in nuclear accumulation of CCNB1 in interphase and premature mitotic entry. May have an antiapoptotic role in NPM-ALK-mediated signaling events.

    Gene: ZC3HC1

    Molekulargewicht
    55kDa
    Gen-ID
    51530
    UniProt
    Q86WB0
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