ZC3HC1 Antikörper (C-Term)
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- Target Alle ZC3HC1 Antikörper anzeigen
- ZC3HC1 (Zinc Finger, C3HC-Type Containing 1 (ZC3HC1))
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Bindungsspezifität
- C-Term
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser ZC3HC1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- Spezifität
- NIPA Antibody detects endogenous levels of total NIPA.
- Homologie
- Pig,Bovine,Horse,Sheep,Rabbit,Dog
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human NIPA, corresponding to a region within C-terminal amino acids.
- Isotyp
- IgG
- Top Product
- Discover our top product ZC3HC1 Primärantikörper
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- Applikationshinweise
- WB 1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
- Haltbarkeit
- 12 months
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- Target
- ZC3HC1 (Zinc Finger, C3HC-Type Containing 1 (ZC3HC1))
- Andere Bezeichnung
- ZC3HC1 (ZC3HC1 Produkte)
- Synonyme
- 1110054L24Rik antikoerper, AU018540 antikoerper, AU019789 antikoerper, HSPC216 antikoerper, Nipa antikoerper, NIPA antikoerper, RGD1561099 antikoerper, zinc finger, C3HC type 1 antikoerper, zinc finger C3HC-type containing 1 antikoerper, zinc finger, C3HC-type containing 1 antikoerper, Zc3hc1 antikoerper, ZC3HC1 antikoerper
- Hintergrund
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Description: Essential component of a SCF-type E3 ligase complex, SCF(NIPA), a complex that controls mitotic entry by mediating ubiquitination and subsequent degradation of cyclin B1 (CCNB1). Its cell-cycle-dependent phosphorylation regulates the assembly of the SCF(NIPA) complex, restricting CCNB1 ubiquitination activity to interphase. Its inactivation results in nuclear accumulation of CCNB1 in interphase and premature mitotic entry. May have an antiapoptotic role in NPM-ALK-mediated signaling events.
Gene: ZC3HC1
- Molekulargewicht
- 55kDa
- Gen-ID
- 51530
- UniProt
- Q86WB0
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