NFATC2IP Antikörper (Internal Region)

Produktnummer ABIN6263627

Produktdetails anti-NFATC2IP Antikörper

Target: NFATC2IP (Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 2 Interacting Protein (NFATC2IP))

Bindungsspezifität: Internal Region

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NFATC2IP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Spezifität: NFATc2IP Antibody detects endogenous levels of total NFATc2IP.

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human NFATc2IP, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu NFATC2IP

Target: NFATC2IP (Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 2 Interacting Protein (NFATC2IP))

Andere Bezeichnung: NFATC2IP (NFATC2IP Produkte)

Synonyme: wu:fj84d09 antikoerper, NFATC2IP antikoerper, D7Ertd304e antikoerper, NIP45 antikoerper, ESC2 antikoerper, RAD60 antikoerper, nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 interacting protein antikoerper, nuclear factor of activated T-cells 2 interacting protein antikoerper, nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2 interacting protein antikoerper, nfatc2ip antikoerper, NFATC2IP antikoerper, Nfatc2ip antikoerper

Hintergrund:

Description: In T-helper 2 (Th2) cells, regulates the magnitude of NFAT-driven transcription of a specific subset of cytokine genes, including IL3, IL4, IL5 and IL13, but not IL2. Recruits PRMT1 to the IL4 promoter, this leads to enhancement of histone H4 'Arg-3'-methylation and facilitates subsequent histone acetylation at the IL4 locus, thus promotes robust cytokine expression (By similarity). Down-regulates formation of poly-SUMO chains by UBE2I/UBC9 (By similarity).

Gene: NFATC2IP

Molekulargewicht: 48kDa

Gen-ID: 84901

UniProt: Q8NCF5