NEK6 Antikörper (Internal Region)

Produktnummer ABIN6263593

Produktdetails anti-NEK6 Antikörper

Target: NEK6 (NIMA (Never in Mitosis Gene A)-Related Kinase 6 (NEK6))

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NEK6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Spezifität: NEK6 Antibody detects endogenous levels of total NEK6.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human NEK6, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu NEK6

Target: NEK6 (NIMA (Never in Mitosis Gene A)-Related Kinase 6 (NEK6))

Andere Bezeichnung: NEK6 (NEK6 Produkte)

Synonyme: 1300007C09Rik antikoerper, si:ch211-167p9.4 antikoerper, ATNEK5 antikoerper, MOE17.17 antikoerper, NIMA-RELATED KINASE5 antikoerper, NIMA-related kinase 5 antikoerper, SID6-1512 antikoerper, NIMA (never in mitosis gene a)-related expressed kinase 6 antikoerper, NIMA-related kinase 6 antikoerper, NIMA related kinase 6 antikoerper, Serine/Threonine kinase catalytic domain protein antikoerper, NIMA-related kinase 6 S homeolog antikoerper, Nek6 antikoerper, nek6 antikoerper, NEK6 antikoerper, NEK5 antikoerper, nek6.S antikoerper

Hintergrund:

Description: Protein kinase which plays an important role in mitotic cell cycle progression. Required for chromosome segregation at metaphase-anaphase transition, robust mitotic spindle formation and cytokinesis. Phosphorylates ATF4, CIR1, PTN, RAD26L, RBBP6, RPS7, RPS6KB1, TRIP4, STAT3 and histones H1 and H3. Phosphorylates KIF11 to promote mitotic spindle formation. Involved in G2/M phase cell cycle arrest induced by DNA damage. Inhibition of activity results in apoptosis. May contribute to tumorigenesis by suppressing p53/TP53-induced cancer cell senescence.

Gene: NEK6

Molekulargewicht: 36 kDa

Gen-ID: 10783

UniProt: Q9HC98