SCN1A Antikörper (Internal Region)

Produktnummer ABIN6263501

Produktdetails anti-SCN1A Antikörper

Target: SCN1A (Sodium Channel, Voltage-Gated, Type I, alpha Subunit (SCN1A))

Bindungsspezifität: Internal Region

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SCN1A Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB)

Spezifität: Nav1.1 Antibody detects endogenous levels of total Nav1.1.

Homologie: Bovine,Horse,Sheep,Rabbit,Chicken

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human Nav1.1, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu SCN1A

Target: SCN1A (Sodium Channel, Voltage-Gated, Type I, alpha Subunit (SCN1A))

Andere Bezeichnung: SCN1A (SCN1A Produkte)

Synonyme: SCN9A antikoerper, SCN1A antikoerper, B230332M13 antikoerper, Nav1.1 antikoerper, EIEE6 antikoerper, FEB3 antikoerper, FEB3A antikoerper, FHM3 antikoerper, GEFSP2 antikoerper, HBSCI antikoerper, NAC1 antikoerper, SCN1 antikoerper, SMEI antikoerper, sodium voltage-gated channel alpha subunit 1 antikoerper, sodium voltage-gated channel alpha subunit 9 antikoerper, sodium channel, voltage-gated, type I, alpha antikoerper, SCN1A antikoerper, SCN9A antikoerper, Scn1a antikoerper

Hintergrund:

Description: Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na+ ions may pass in accordance with their electrochemical gradient. Plays a key role in brain, probably by regulating the moment when neurotransmitters are released in neurons. Involved in sensory perception of mechanical pain: activation in somatosensory neurons induces pain without neurogenic inflammation and produces hypersensitivity to mechanical, but not thermal stimuli.

Gene: SCN1A

Molekulargewicht: 228 kDa

Gen-ID: 6323

UniProt: P35498