MBP Antikörper

Produktnummer ABIN6263152

Produktdetails anti-MBP Antikörper

Target: MBP (Myelin Basic Protein (MBP))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MBP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Spezifität: MBP Antibody detects endogenous levels of total MBP

Kreuzreaktivität: Human, Maus, Ratte (Rattus)

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human MBP

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000 IHC 1:50-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C.Stable for 12 months from date of receipt

Haltbarkeit: 12 months

Details zu MBP

Target: MBP (Myelin Basic Protein (MBP))

Andere Bezeichnung: Myelin basic protein (MBP Produkte)

Synonyme: C76307 antikoerper, Hmbpr antikoerper, R75289 antikoerper, golli-mbp antikoerper, mld antikoerper, shi antikoerper, Mbps antikoerper, cb274 antikoerper, fj33b11 antikoerper, mbp antikoerper, wu:fj33b11 antikoerper, wu:fq15b02 antikoerper, zgc:136630 antikoerper, MGC115135 antikoerper, myelin basic protein antikoerper, myelin basic protein a antikoerper, myelin basic protein L homeolog antikoerper, MBP antikoerper, Mbp antikoerper, mbpa antikoerper, mbp antikoerper, mbp.L antikoerper

Hintergrund:

Description: The classic group of MBP isoforms (isoform 4-isoform 14) are with PLP the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The smaller isoforms might have an important role in remyelination of denuded axons in multiple sclerosis. The non-classic group of MBP isoforms (isoform 1-isoform 3/Golli-MBPs) may preferentially have a role in the early developing brain long before myelination, maybe as components of transcriptional complexes, and may also be involved in signaling pathways in T-cells and neural cells. Differential splicing events combined with optional post-translational modifications give a wide spectrum of isomers, with each of them potentially having a specialized function. Induces T-cell proliferation.

Gene: MBP

Molekulargewicht: 33kDa

Gen-ID: 4155

UniProt: P02686