MAGT1 Antikörper (Internal Region)

Produktnummer ABIN6263082

Produktdetails anti-MAGT1 Antikörper

Target: MAGT1 (Magnesium Transporter 1 (MAGT1))

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MAGT1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Spezifität: MAGT1 Antibody detects endogenous levels of total MAGT1.

Homologie: Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human MAGT1, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC 1:50-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu MAGT1

Target: MAGT1 (Magnesium Transporter 1 (MAGT1))

Andere Bezeichnung: MAGT1 (MAGT1 Produkte)

Synonyme: IAP antikoerper, MRX95 antikoerper, OST3B antikoerper, PRO0756 antikoerper, XMEN antikoerper, bA217H1.1 antikoerper, 2410001C15Rik antikoerper, 2610529C04Rik antikoerper, 2810482I07Rik antikoerper, IAG2 antikoerper, Iag2 antikoerper, magnesium transporter 1 antikoerper, MAGT1 antikoerper, Magt1 antikoerper

Hintergrund:

Description: Acts as accessory component of the N-oligosaccharyl transferase (OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains. Involved in N-glycosylation of STT3B-dependent substrates. Specifically required for the glycosylation of a subset of acceptor sites that are near cysteine residues, in this function seems to act redundantly with TUSC3. In its oxidized form proposed to form transient mixed disulfides with a glycoprotein substrate to facilitate access of STT3B to the unmodified acceptor site. Has also oxidoreductase-independent functions in the STT3B-containing OST complex possibly involving substrate recognition.

Gene: MAGT1

Molekulargewicht: 45-47 kDa

Gen-ID: 84061

UniProt: Q9H0U3

Pathways: Cell RedoxHomeostasis