KMO Antikörper (Internal Region)
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- Target Alle KMO Antikörper anzeigen
- KMO (Kynurenine 3-Monooxygenase (Kynurenine 3-Hydroxylase) (KMO))
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Bindungsspezifität
- Internal Region
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser KMO Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC)
- Spezifität
- KMO Antibody detects endogenous levels of total KMO.
- Homologie
- Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human KMO, corresponding to a region within the internal amino acids.
- Isotyp
- IgG
- Top Product
- Discover our top product KMO Primärantikörper
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- Applikationshinweise
- WB 1:500-1:2000, IHC 1:50-1:200
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
- Haltbarkeit
- 12 months
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- Target
- KMO (Kynurenine 3-Monooxygenase (Kynurenine 3-Hydroxylase) (KMO))
- Andere Bezeichnung
- KMO (KMO Produkte)
- Synonyme
- AI046660 antikoerper, dJ317G22.1 antikoerper, kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) antikoerper, kynurenine 3-monooxygenase antikoerper, Kmo antikoerper, KMO antikoerper
- Hintergrund
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Description: Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn) (PubMed:29429898, PubMed:23575632, PubMed:26752518, PubMed:28604669, PubMed:29208702). Required for synthesis of quinolinic acid, a neurotoxic NMDA receptor antagonist and potential endogenous inhibitor of NMDA receptor signaling in axonal targeting, synaptogenesis and apoptosis during brain development. Quinolinic acid may also affect NMDA receptor signaling in pancreatic beta cells, osteoblasts, myocardial cells, and the gastrointestinal tract (Probable).
Gene: KMO
- Molekulargewicht
- 55.8 kDa
- Gen-ID
- 8564
- UniProt
- O15229
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