KCNJ10 Antikörper (Internal Region)

Produktnummer ABIN6262748

Produktdetails anti-KCNJ10 Antikörper

Target: KCNJ10 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 10 (KCNJ10))

Bindungsspezifität: Internal Region

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KCNJ10 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Spezifität: KCNJ10 Antibody detects endogenous levels of total KCNJ10.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog,Xenopus

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human KCNJ10, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-3000, IHC 1:200, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu KCNJ10

Target: KCNJ10 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 10 (KCNJ10))

Andere Bezeichnung: KCNJ10 (KCNJ10 Produkte)

Synonyme: kir1.2 antikoerper, kir4.1 antikoerper, birk-10 antikoerper, MGC145926 antikoerper, BIR10 antikoerper, BIRK-1 antikoerper, Kir1.2 antikoerper, Kir4.1 antikoerper, BIRK-10 antikoerper, KCNJ13-PEN antikoerper, KIR1.2 antikoerper, KIR4.1 antikoerper, SESAME antikoerper, potassium channel, inwardly rectifying subfamily J, member 10 L homeolog antikoerper, potassium voltage-gated channel subfamily J member 10 antikoerper, potassium channel, inwardly rectifying subfamily J, member 10 antikoerper, potassium inwardly-rectifying channel, subfamily J, member 10 antikoerper, kcnj10.L antikoerper, KCNJ10 antikoerper, kcnj10 antikoerper, Kcnj10 antikoerper

Hintergrund:

Description: May be responsible for potassium buffering action of glial cells in the brain. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium, as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium and cesium (By similarity). In the kidney, together with KCNJ16, mediates basolateral K+ recycling in distal tubules, this process is critical for Na+ reabsorption at the tubules.

Gene: KCNJ10

Molekulargewicht: 43 kDa

Gen-ID: 3766

UniProt: P78508

Pathways: Dicarboxylic Acid Transport, Regulation of long-term Neuronal Synaptic Plasticity