Kcne3 Antikörper (Internal Region)

Produktnummer ABIN6262743

Produktdetails anti-Kcne3 Antikörper

Target: Kcne3 (Potassium Voltage-Gated Channel, Isk-Related Family, Member 3 (Kcne3))

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Kcne3 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC), Western Blotting (WB)

Spezifität: KCNE3 Antibody detects endogenous levels of total KCNE3.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human KCNE3, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-3000, IHC 1:200, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu Kcne3

Target: Kcne3 (Potassium Voltage-Gated Channel, Isk-Related Family, Member 3 (Kcne3))

Andere Bezeichnung: KCNE3 (Kcne3 Produkte)

Synonyme: HOKPP antikoerper, HYPP antikoerper, MiRP2 antikoerper, 2210017H05Rik antikoerper, potassium voltage-gated channel subfamily E regulatory subunit 3 antikoerper, potassium voltage-gated channel, Isk-related subfamily, gene 3 antikoerper, KCNE3 antikoerper, Kcne3 antikoerper

Hintergrund:

Description: Ancillary protein that assembles as a beta subunit with a voltage-gated potassium channel complex of pore-forming alpha subunits. Modulates the gating kinetics and enhances stability of the channel complex. Assembled with KCNB1 modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1 (PubMed:12954870). Associated with KCNC4/Kv3.4 is proposed to form the subthreshold voltage-gated potassium channel in skeletal muscle and to establish the resting membrane potential (RMP) in muscle cells. Associated with KCNQ1/KCLQT1 may form the intestinal cAMP-stimulated potassium channel involved in chloride secretion that produces a current with nearly instantaneous activation with a linear current-voltage relationship.

Gene: KCNE3

Molekulargewicht: 12 kDa

Gen-ID: 10008

UniProt: Q9Y6H6