AIMP2 Antikörper (Internal Region)

Produktnummer ABIN6262712

Produktdetails anti-AIMP2 Antikörper

Target: AIMP2 (Aminoacyl tRNA Synthetase Complex-Interacting Multifunctional Protein 2 (AIMP2))

Bindungsspezifität: Internal Region

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AIMP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Spezifität: AIMP2/p38 Antibody detects endogenous levels of total AIMP2/p38.

Homologie: Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human AIMP2/p38, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC 1:50-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu AIMP2

Target: AIMP2 (Aminoacyl tRNA Synthetase Complex-Interacting Multifunctional Protein 2 (AIMP2))

Andere Bezeichnung: AIMP2 (AIMP2 Produkte)

Synonyme: jtv1 antikoerper, MGC53242 antikoerper, pro0992 antikoerper, JTV1 antikoerper, JTV-1 antikoerper, P38 antikoerper, AA407136 antikoerper, AA407225 antikoerper, Aimp2(p38) antikoerper, Jtv1 antikoerper, aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 L homeolog antikoerper, aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 antikoerper, aminoacyl tRNA synthetase complex interacting multifunctional protein 2 antikoerper, aimp2.L antikoerper, aimp2 antikoerper, AIMP2 antikoerper, Aimp2 antikoerper

Hintergrund:

Description: Required for assembly and stability of the aminoacyl-tRNA synthase complex (PubMed:19131329). Mediates ubiquitination and degradation of FUBP1, a transcriptional activator of MYC, leading to MYC down-regulation which is required for aveolar type II cell differentiation. Blocks MDM2-mediated ubiquitination and degradation of p53/TP53. Functions as a proapoptotic factor.

Gene: AIMP2

Molekulargewicht: 36 kDa

Gen-ID: 7965

UniProt: Q13155