HSD17B12 Antikörper (Internal Region)

Produktnummer ABIN6262377

Produktdetails anti-HSD17B12 Antikörper

Target: HSD17B12 (Hydroxysteroid (17-Beta) Dehydrogenase 12 (HSD17B12))

Bindungsspezifität: Internal Region

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HSD17B12 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Spezifität: HSD17B12 Antibody detects endogenous levels of total HSD17B12.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human HSD17B12, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu HSD17B12

Target: HSD17B12 (Hydroxysteroid (17-Beta) Dehydrogenase 12 (HSD17B12))

Andere Bezeichnung: HSD17B12 (HSD17B12 Produkte)

Synonyme: KAR antikoerper, SDR12C1 antikoerper, 2610510O05Rik antikoerper, AI172963 antikoerper, KIK-I antikoerper, Kik1 antikoerper, HSD17B12 antikoerper, kar antikoerper, sdr12c1 antikoerper, 17-beta-HSD 12-A antikoerper, fi06g11 antikoerper, wu:fi06g11 antikoerper, zf3.1 antikoerper, zfHSD17B12A antikoerper, zgc:55589 antikoerper, zgc:77599 antikoerper, hydroxysteroid 17-beta dehydrogenase 12 antikoerper, hydroxysteroid (17-beta) dehydrogenase 12 antikoerper, hydroxysteroid (17-beta) dehydrogenase 12 L homeolog antikoerper, hydroxysteroid (17-beta) dehydrogenase 12a antikoerper, HSD17B12 antikoerper, Hsd17b12 antikoerper, hsd17b12.L antikoerper, hsd17b12a antikoerper

Hintergrund:

Description: Catalyzes the second of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme has a 3-ketoacyl-CoA reductase activity, reducing 3-ketoacyl-CoA to 3-hydroxyacyl-CoA, within each cycle of fatty acid elongation. Thereby, it may participate in the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators. May also catalyze the transformation of estrone (E1) into estradiol (E2) and play a role in estrogen formation.

Gene: HSD17B12

Molekulargewicht: 34 kDa

Gen-ID: 51144

UniProt: Q53GQ0

Pathways: Steroid Hormone Biosynthesis