HSD17B10 Antikörper (Internal Region)

Produktnummer ABIN6262376

Produktdetails anti-HSD17B10 Antikörper

Target: HSD17B10 (Hydroxysteroid (17-Beta) Dehydrogenase 10 (HSD17B10))

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HSD17B10 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Spezifität: ERAB Antibody detects endogenous levels of total ERAB.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human ERAB, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu HSD17B10

Target: HSD17B10 (Hydroxysteroid (17-Beta) Dehydrogenase 10 (HSD17B10))

Andere Bezeichnung: HSD17B10 (HSD17B10 Produkte)

Synonyme: hadh2 antikoerper, im:6899159 antikoerper, wu:fj61f03 antikoerper, zgc:101605 antikoerper, abad antikoerper, camr antikoerper, erab antikoerper, hcd2 antikoerper, hsd10 antikoerper, mhbd antikoerper, mrpp2 antikoerper, mrx17 antikoerper, mrx31 antikoerper, mrxs10 antikoerper, schad antikoerper, sdr5c1 antikoerper, HADH2 antikoerper, HSD17B10 antikoerper, 17b-HSD10 antikoerper, ABAD antikoerper, CAMR antikoerper, DUPXp11.22 antikoerper, ERAB antikoerper, HCD2 antikoerper, MHBD antikoerper, MRPP2 antikoerper, MRX17 antikoerper, MRX31 antikoerper, MRXS10 antikoerper, SCHAD antikoerper, SDR5C1 antikoerper, 17bHSD10 antikoerper, Ads9 antikoerper, Hadh2 antikoerper, hydroxysteroid (17-beta) dehydrogenase 10 antikoerper, hydroxysteroid 17-beta dehydrogenase 10 antikoerper, hydroxysteroid (17-beta) dehydrogenase 10 L homeolog antikoerper, HSD17B10 antikoerper, hsd17b10 antikoerper, hsd17b10.L antikoerper, Hsd17b10 antikoerper

Hintergrund:

Description: Mitochondrial dehydrogenase that catalyzes the beta-oxidation at position 17 of androgens and estrogens and has 3-alpha-hydroxysteroid dehydrogenase activity with androsterone (PubMed:9553139, PubMed:23042678, PubMed:12917011, PubMed:18996107, PubMed:25925575, PubMed:28888424). Catalyzes the third step in the beta-oxidation of fatty acids (PubMed:9553139, PubMed:12917011, PubMed:18996107, PubMed:25925575, PubMed:28888424). Carries out oxidative conversions of 7-alpha-OH and 7-beta-OH bile acids (PubMed:12917011). Also exhibits 20-beta-OH and 21-OH dehydrogenase activities with C21 steroids (PubMed:12917011). By interacting with intracellular amyloid-beta, it may contribute to the neuronal dysfunction associated with Alzheimer disease (AD) (PubMed:9338779). Essential for structural and functional integrity of mitochondria (PubMed:20077426).

Gene: HSD17B10

Molekulargewicht: 27kDa

Gen-ID: 3028

UniProt: Q99714