GCKR Antikörper (Internal Region)
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- Target Alle GCKR Antikörper anzeigen
- GCKR (Glucokinase (Hexokinase 4) Regulator (GCKR))
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Bindungsspezifität
- Internal Region
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Reaktivität
- Human, Ratte, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser GCKR Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Spezifität
- GCKR Antibody detects endogenous levels of total GCKR.
- Homologie
- Pig,Rabbit,Dog
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human GCKR, corresponding to a region within the internal amino acids.
- Isotyp
- IgG
- Top Product
- Discover our top product GCKR Primärantikörper
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- Applikationshinweise
- WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
- Haltbarkeit
- 12 months
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- Target
- GCKR (Glucokinase (Hexokinase 4) Regulator (GCKR))
- Andere Bezeichnung
- GCKR (GCKR Produkte)
- Synonyme
- FGQTL5 antikoerper, GKRP antikoerper, GLRE antikoerper, gckr antikoerper, glucokinase regulator antikoerper, glucokinase regulatory protein antikoerper, glucokinase regulator L homeolog antikoerper, GCKR antikoerper, Gckr antikoerper, gckr.L antikoerper
- Hintergrund
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Description: Inhibits glucokinase (GCK) by forming an inactive complex with this enzyme. The affinity of GCKR for GCK is modulated by fructose metabolites: GCKR with bound fructose 6-phosphate has increased affinity for GCK, while GCKR with bound fructose 1-phosphate has strongly decreased affinity for GCK and does not inhibit GCK activity.
Gene: GCKR
- Molekulargewicht
- 68kDa
- Gen-ID
- 2646
- UniProt
- Q14397
- Pathways
- Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus
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