FAF2 Antikörper (Internal Region)

Produktnummer ABIN6261659

Produktdetails anti-FAF2 Antikörper

Target: FAF2 (Fas Associated Factor Family Member 2 (FAF2))

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FAF2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Spezifität: FAF2 Antibody detects endogenous levels of total FAF2.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human FAF2, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC 1:50-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu FAF2

Target: FAF2 (Fas Associated Factor Family Member 2 (FAF2))

Andere Bezeichnung: FAF2 (FAF2 Produkte)

Synonyme: FAF2 antikoerper, UBXD8 antikoerper, ETEA antikoerper, UBXN3B antikoerper, 2210404D11Rik antikoerper, AI462440 antikoerper, Ubxd8 antikoerper, mKIAA0887 antikoerper, 2210404d11rik antikoerper, RGD1306577 antikoerper, UBX8 antikoerper, etea antikoerper, ubxd8 antikoerper, ubxn3b antikoerper, Fas associated factor family member 2 antikoerper, Fas associated factor family member 2 S homeolog antikoerper, FAF2 antikoerper, Faf2 antikoerper, faf2.S antikoerper

Hintergrund:

Description: Plays an important role in endoplasmic reticulum-associated degradation (ERAD) that mediates ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins (PubMed:18711132, PubMed:24215460). By controlling the steady-state expression of the IGF1R receptor, indirectly regulates the insulin-like growth factor receptor signaling pathway (PubMed:26692333). Involved in inhibition of lipid droplet degradation by binding to phospholipase PNPL2 and inhibiting its activity by promoting dissociation of PNPL2 from its endogenous activator, ABHD5 which inhibits the rate of triacylglycerol hydrolysis (PubMed:23297223).

Gene: FAF2

Molekulargewicht: 53 kDa

Gen-ID: 23197

UniProt: Q96CS3