EDEM2 Antikörper

Produktnummer ABIN6261430

Produktdetails anti-EDEM2 Antikörper

Target: EDEM2 (ER Degradation Enhancer, Mannosidase alpha-Like 2 (EDEM2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EDEM2 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB)

Spezifität: EDEM2 Antibody detects endogenous levels of total EDEM2

Kreuzreaktivität: Human

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human EDEM2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-3000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C.Stable for 12 months from date of receipt

Haltbarkeit: 12 months

Details zu EDEM2

Target: EDEM2 (ER Degradation Enhancer, Mannosidase alpha-Like 2 (EDEM2))

Andere Bezeichnung: EDEM2 (EDEM2 Produkte)

Synonyme: C20orf31 antikoerper, C20orf49 antikoerper, bA4204.1 antikoerper, 9530090G24Rik antikoerper, AI327354 antikoerper, RGD1303074 antikoerper, MGC88910 antikoerper, DKFZp459A0314 antikoerper, ER degradation enhancing alpha-mannosidase like protein 2 antikoerper, ER degradation enhancer, mannosidase alpha-like 2 antikoerper, EDEM2 antikoerper, Edem2 antikoerper, edem2 antikoerper

Hintergrund:

Description: Initiates the endoplasmic reticulum-associated degradation (ERAD) that targets misfolded glycoproteins for degradation in an N-glycan-dependent manner. Catalyzes the first mannose trimming step, from Man9GlcNAc2 to Man8GlcNAc2 (PubMed:25092655). Extracts misfolded glycoproteins, but not glycoproteins undergoing productive folding, from the calnexin cycle.

Gene: EDEM2

Molekulargewicht: 65 kDa

Gen-ID: 55741

UniProt: Q9BV94